GATA3 (Ser162) Antibody

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Catalog number: bs-10280R
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies.
Product name: GATA3 (Ser162) Antibody
Quantity: 100ul
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Long name: GATA3 (Ser162) Primary Polyclonal Antibody
Also known as: GATA3 (Ser162) PAb
Category: Primary Antibodies
Conjugation: Unconjugated
Target Antigen: GATA3 Ser162
Specificity: This is a highly specific antibody against GATA3 Ser162
Modification(s): Phosphorylation
Modification site(s): Ser162
Clonality: Polyclonal antibody
Clone number: Polyclonal antibody
Concentration: 1ug per 1ul
Subcellular location: Helical, Extracellular
Source: KLH conjugated synthetic phosphopeptide derived from human GATA3 around the phosphorylation site of Ser162
Gene ID number: 2625
Tested Applications: IF(IHC-P), IHC-P, WB
Recommended dilutions: IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity: Mouse, Rat, Human
Cross reactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen: AGATCTTA, Although expression patterns of the various GATA transcription factors may overlap, Both GATA-4 and GATA-6 are found in heart, GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes, GATA-2 is expressed in embryonic brain and liver, GATA-3 is highly expressed in T lymphocytes, GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors, GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart, HeLa and endothelial cells, It is an essential component in the generation of the erythroid lineage, Studies with a modified GATA consensus sequence, This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1, as well as in erythroid cells, but not GATA-4 expression, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites, lung and liver tissues exhibit GATA-6, pancreas and ovary, Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names: GATA 3, GATA binding factor 3, GATA binding protein 3, GATA-3, GATA-binding factor 3, GATA3, GATA3 phospho Ser162, GATA3_HUMAN, HDR, MGC2346, MGC5199, MGC5445, Trans acting T cell specic transcription factor GATA 3, Trans-acting T-cell-specic transcription factor GATA-3, p-GATA3 Ser162, p-GATA3 phospho S162, GATA3 phospho S162
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target: GATA3 (Ser162)
Short name: GATA3 (Ser162) Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: GATA3 (Ser162) (Antibody to)
Alternative technique: antibodies
Identity: 4172
Gene: GATA3 | More about : GATA3
Long gene name: GATA binding protein 3
Synonyms gene name: GATA-binding protein 3
Synonyms: HDR
Locus: 10p14
Discovery year: 1992-11-03
GenBank acession: X55122
Entrez gene record: 2625
Pubmed identfication: 2050118 15087456
RefSeq identity: NM_001002295
Classification: GATA zinc finger domain containing
Havana BLAST/BLAT: OTTHUMG00000017640

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