| Long name: |
Cy7 Conjugated, MHC class I Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MHC class I |
| Specificity: |
This is a highly specific antibody against MHC class I |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
60-105/181 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human MHC class I |
| Swiss Prot: |
G0ZMJ8 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen, Exon 1 encodes the leader peptide, Hundreds of HLA-A alleles have been described, Jul 2008], Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule, The heavy chain is anchored in the membrane, The heavy chain is approximately 45 kDa and its gene contains 8 exons, They are expressed in nearly all cells, This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin), Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation, [provided by RefSeq, and exons 6 and 7 encode the cytoplasmic tail, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, HLA-A belongs to the HLA class I heavy chain paralogues |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
1C04_HUMAN, A 9, Aw 24, Aw 68, CLASS I HISTOCOMPATIBILITY ANTIGEN, H2 K1, H2K, HLA A, HLA C, HLA class I histocompatibility antigen A 1 alpha chain, HLA class I histocompatibility antigen A 11 alpha chain, HLA class I histocompatibility antigen A 2 alpha chain, HLA class I histocompatibility antigen A 24 alpha chain, HLA class I histocompatibility antigen A 3 alpha chain, HLA class I histocompatibility antigen A 30 alpha chain, HLA class I histocompatibility antigen A 32 alpha chain, HLA class I histocompatibility antigen A 68 alpha chain, HLA-A, HLA-C, HLAA, MHC class I heavy chain H2 K, Major histocompatibility complex class I A, A 28 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
MHC class I Conjugated |
| Short name: |
Conjugated, MHC class I Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, Major histocompabitility complex class I (Antibody to) |
| Alternative technique: |
antibodies |