| Long name: |
HPV58 E6 Primary Polyclonal Antibody |
| Also known as: |
HPV58 E6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HPV58 E6 |
| Specificity: |
This antibody will also detect E6 in HPV33 and Alphapapillomavirus 9, This is a highly specific antibody against HPV58 E6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from HPV58 E6 protein |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Virus |
| Cross reactive species details: |
HPV58 |
| Background of the target antigen: |
31 and 33, Approximately 90% of cervical cancers contain HPV DNA of the high risk types, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, However, Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, have been confirmed as agents which cause cervical cancer, notably types 16 and 18, respectively, some subtypes, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E6 protein HPV58, HPV58 E6 protein, HPV58-E6 protein, Human Papilloma Virus, Human papillomavirus type 58, Human papillomavirus type 58, Protein 58, VE6_HPV58, E6 protein [Human papillomavirus type 58] |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HPV58 E6 |
| Short name: |
HPV58 E6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HPV58 E6 (Antibody to) |
| Alternative technique: |
antibodies |