| Long name: |
ALEXA FLUOR 350 Conjugated, Eph receptor B1 (Tyr928) Antibody |
| Also known as: |
Anti-Eph receptor B1 Tyr928 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Eph receptor B1 Tyr928 |
| Specificity: |
This is a highly specific antibody against Eph receptor B1 Tyr928 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr928 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
910-950/984 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human EphB1 around the phosphorylation site of Tyr928 |
| Gene ID Number: |
2047 |
| Swiss Prot: |
P54762 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cognate/functional ephrin ligands for this receptor include EFNB1, During nervous system development, EFNB2 and EFNB3, In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation, In the adult nervous system together with EFNB3, May also regulate angiogenesis, More generally, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, This probably requires repulsive interaction with EFNB2, Upon activation by EFNB1 and probably other ephrin-B ligands activates the MAPK/ERK and the JNK signaling cascades to regulate cell migration and adhesion respectively, leading to contact-dependent bidirectional signaling into neighboring cells, may play a role in targeted cell migration and adhesion, proliferation and polarity of the hippocampus neural progenitors, regulates chemotaxis, regulates retinal axon guidance redirecting ipsilaterally ventrotemporal retinal ganglion cells axons at the optic chiasm midline, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
EK6, EPH tyrosine kinase 2, EPH-like kinase 6, EPHB1, EPHT2, Ephrin type-B receptor 1, Hek6, NET, Neuronally-expressed EPH-related tyrosine kinase, Tyrosine-protein kinase receptor EPH-2, ELK |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
Eph receptor B1 (Tyr928) |
| Short name: |
Eph receptor B1 (Tyr928) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Eph receptor B1 (Tyr928) (Antibody to) |
| Alternative technique: |
antibodies |