| Long name: |
P21 Primary Polyclonal Antibody |
| Also known as: |
P21 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
P21 |
| Specificity: |
This is a highly specific antibody against P21 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
13-41/164 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P21 |
| Gene ID number: |
1026 |
| Swiss Prot: |
P38936 |
| Tested Applications: |
IF(ICC), IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
At higher stoichiometric ratios, Binds to and inhibits cyclin-dependent kinase activity, Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1, inhibits the kinase activity of the cyclin D-CDK4 complex, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression, May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAP2, CDK-interacting protein 1, CDKN1, CDKN1A, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation-associated protein 6, PIC1, SDI1, WAF1, p21CIP1, P21 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
P21 |
| Short name: |
P21 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
P21 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11616 |
| Gene: |
TCEAL1 |
More about : TCEAL1 |
| Long gene name: |
transcription elongation factor A like 1 |
| Synonyms gene name: |
transcription elongation factor A (SII)-like 1 |
| Synonyms: |
p21 pp21 SIIR P21 WEX9 |
| Locus: |
Xq22, 2 |
| Discovery year: |
1998-09-21 |
| GenBank acession: |
M99701 |
| Entrez gene record: |
9338 |
| Pubmed identfication: |
8206389 7971997 16221301 |
| RefSeq identity: |
NM_004780 |
| Classification: |
Transcription elongation factor A like family |
| Havana BLAST/BLAT: |
OTTHUMG00000022699 |