| Long name: |
SLC7A5 Primary Polyclonal Antibody |
| Also known as: |
SLC7A5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SLC7A5 |
| Specificity: |
This is a highly specific antibody against SLC7A5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-140/507 |
| Subcellular location: |
Transmembrane, Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC7A5 |
| Gene ID number: |
8140 |
| Swiss Prot: |
Q01650 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as an amino acid exchanger, Acts as the major transporter of tyrosine in fibroblasts, Involved in cellular amino acid uptake, Involved in the cellular activity of small molecular weight nitrosothiols, Involved in the transport of L-DOPA across the blood-brain barrier, Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D, May play an important role in high-grade gliomas, Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina, Plays a role in neuronal cell proliferation (neurogenesis) in brain, and hence plays a role in metal ion homeostasis and toxicity, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta, arginine and tryptophan, high-affinity transport of large neutral amino acids such as phenylalanine, leucine, tyrosine, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane, when associated with SLC3A2/4F2hc, L-homocysteine complexes, Sodium-independent |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
4F2 LC, 4F2 light chain, 4F2LC, CD98 light chain, CD98LC, Integral membrane protein E16, L-type amino acid transporter 1, LAT1, MPE16, SLC7A5, Solute carrier family 7 member 5, hLAT1, y+ system cationic amino acid transporter, Large neutral amino acids transporter small subunit 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLC7A5 |
| Short name: |
SLC7A5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLC7A5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11063 |
| Gene: |
SLC7A5 |
More about : SLC7A5 |
| Long gene name: |
solute carrier family 7 member 5 |
| Synonyms gene name: |
L system), member 5 , solute carrier family 7 (amino acid transporter light chain |
| Synonyms: |
LAT1 E16 D16S469E MPE16 CD98 |
| Locus: |
16q24, 2 |
| Discovery year: |
1999-01-28 |
| GenBank acession: |
AF077866 |
| Entrez gene record: |
8140 |
| Pubmed identfication: |
9751058 7829099 |
| RefSeq identity: |
NM_003486 |
| Classification: |
Solute carriers CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000137658 |