| Long name: |
Fibrinogen beta chain Antibody |
| Also known as: |
Fibrinogen beta chain Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Fibrinogen beta chain |
| Specificity: |
This is a highly specific antibody against Fibrinogen beta chain |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
420-470/491 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fibrinogen beta chain |
| Gene ID number: |
2244 |
| Swiss Prot: |
P02675 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Enhances expression of SELP in activated platelets, Fibrin deposition is also associated with infection, Fibrin has a major function in hemostasis as one of the primary components of blood clots, However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerize to form an insoluble fibrin matrix, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), where it protects against IFNG-mediated hemorrhage, Cleaved by the protease thrombin to yield monomers which |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FGB, Fibrinogen beta chain, HEL-S-78p |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Fibrinogen beta chain |
| Short name: |
Fibrinogen beta chain Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Fibrinogen b epitope (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3662 |
| Gene: |
FGB |
More about : FGB |
| Long gene name: |
fibrinogen beta chain |
| Synonyms gene name: |
B beta polypeptide , fibrinogen |
| Locus: |
4q31, 3 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2244 |
| RefSeq identity: |
NM_005141 |
| Classification: |
Endogenous ligands Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150331 |
| Locus Specific Databases: |
A Database For Human Fibrinogen Variants LRG_558 |