| Long name: |
ALEXA FLUOR 647 Conjugated, Tau protein(Ser519) Polyclonal Antibody |
| Also known as: |
Anti-Tau protein Ser519 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Tau protein Ser519 |
| Specificity: |
This is a highly specific antibody against Tau protein Ser519 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser519 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser519 |
| Gene ID Number: |
4137 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, It expressed in neurons, PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system, Tau proteins subcellular located in the axons of neurons, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, in the cytoso l and in association with plasma membrane components, suggesting that tau functions as a linker protein between both, Tau proteins are important Promotes microtubule assembly and stability |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
AI413597, AW045860, DDPAC, Disinhibition dementia parkinsonism amyotrophy complex, FLJ31424, FTDP 17, FTDP17, G Protein beta 1 gamma 2 subunit interacting factor 1, G protein beta1/gamma2 subunit interacting factor 1, MAPT, MAPTL, MAPTphospho 519, MGC134287, MGC138549, MGC156663, MSTD, MTBT1, MTBT2, Microtuble-associted protein Tau, Microtubule associated protein tau isoform 4, Mtapt, Neurofibrillary tangle protein, PHF tau, PHF-tau, PPND, Paired helical filament tau, RNPTAU, TAU_HUMAN, Tauopathy and respiratory failure, included, p-Tau proteinSer519, p-TauSer202, pTau, TauSer519 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Tau protein(Ser519) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Tau protein(Ser519) |
| Short name: |
Tau protein(Ser519) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Taurine protein(Ser519) (Antibody to) |
| Alternative technique: |
antibodies |