| Long name: |
Biotin Conjugated, VEGFB Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VEGFB |
| Specificity: |
This is a highly specific antibody against VEGFB |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human VEGFB |
| Gene ID number: |
4902 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Several growth factors with angiogenic activity have been described and include fibroblast growth factor (FGF), The VEGF protein family is comprised of VEGF, VEGF-B, VEGF-B, VEGF-C and VEGF-D, VEGF-C binds to and specifically activates Flt-4 and Flk-1, all of which may exhibit angiogenic function in vivo, is abundantly expressed in heart and skeletal muscle and is frequently co-expressed with VEGF, platelet derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs), which exists as two alternatively spliced isoforms known as VEGF-B167 and VEGF-B186, The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
VEGFL |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VEGFB Conjugated |
| Short name: |
Conjugated, VEGFB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, vascular endothelial growth factor B (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, VEGFB and IDBG-53284 and ENSG00000173511 and 7423, VEGFB and IDBG-643900 and ENSBTAG00000047567 and, VEGFL and VRF, Vegfb and IDBG-137732 and ENSMUSG00000024962 and 22340, protein heterodimerization activity, this GO :0001525 and angiogenesis and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0006493 and protein O-linked glycosylation and biological process this GO :0007507 and heart development and biological process this GO :0007596 and blood coagulation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0010629 and negative regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0035470 and positive regulation of vascular wound healing and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0042493 and response to drug and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043183 and vascular endothelial growth factor receptor 1 binding and molecular function this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048010 and vascular endothelial growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0060754 and positive regulation of mast cell chemotaxis and biological process this GO :0060976 and coronary vasculature development and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0008201 : heparin binding and also this GO :0042056 : chemoattractant activity and also this GO :0042803 : protein homodimerization activity and also this GO :0043183 : vascular endothelial growth factor receptor 1 binding and also this GO :0046982 : protein heterodimerization activity, this GO :0008083 : growth factor activity, this GO :0008201 : heparin binding, this GO :0042056 : chemoattractant activity, this GO :0042803 : protein homodimerization activity, this GO :0043183 : vascular endothelial growth factor receptor 1 binding, this GO :0046982 : protein heterodimerization activity, vascular endothelial growth factor B |
| Identity: |
12681 |
| Gene: |
VEGFB |
More about : VEGFB |
| Long gene name: |
vascular endothelial growth factor B |
| Synonyms gene: |
VRF |
| Locus: |
11q13, 1 |
| Discovery year: |
1996-10-26 |
| GenBank acession: |
BC008818 |
| Entrez gene record: |
7423 |
| Pubmed identfication: |
8637916 8919691 |
| RefSeq identity: |
NM_003377 |
| Classification: |
VEGF family |
| Havana BLAST/BLAT: |
OTTHUMG00000167813 |