| Long name: |
DC-SIGN Primary Polyclonal Antibody |
| Also known as: |
DC-SIGN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DC-SIGN |
| Specificity: |
This is a highly specific antibody against DC-SIGN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DC-SIGN/CD209 |
| Gene ID number: |
30835 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A DC-SIGN homologue (termed CD299, DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR, DC-SIGNR, DCs also amplify the amount of virus and extend the duration of viral infectivity, HIV2 and SIV bind to DCs via DCSIGN, ICAM3 is the natural ligand for DC-SIGN, L-SIGN and DCSIGN2) was identified recently, Multiple strains of HIV1, The expression of DC-SIGN was found in mucosal tissues including placenta, and rectum, small intestine, where DCs hand over HIV to CD4+ T lymphocytes, Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C type lectin domain family 4 member L, CD 209, CD209, CD209 antigen, CD209 antigen-like protein A, CD209 molecule, CD209_HUMAN, CDSIGN, CIRE, Cd209a, DC SIGN1, DCSIGN, Dendritic cell specic ICAM 3 grabbing nonintegrin 1, Dendritic cell specic ICAM3 grabbing nonintegrin 1, Dendritic cell-specic ICAM-3-grabbing non-integrin 1, Dendritic cell-specic intracellular adhesion molecules ICAM-3 grabbing non-integrin, Dengue fever, Dentritic Cell Specic ICAM3 Grabbing Nonintegrin, HIV GP120 Binding Protein, MGC129965, MGC130443, SIGN-R1, SIGNR5, included, protection against, CLEC4L |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DC-SIGN |
| Short name: |
DC-SIGN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DC-SIGN (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1641 |
| Gene: |
CD209 |
More about : CD209 |
| Long gene name: |
CD209 molecule |
| Synonyms gene name: |
CD209 antigen |
| Synonyms: |
DC-SIGN CDSIGN DC-SIGN1 CLEC4L |
| Locus: |
19p13, 2 |
| Discovery year: |
2000-07-19 |
| GenBank acession: |
M98457 |
| Entrez gene record: |
30835 |
| Pubmed identfication: |
1518869 |
| RefSeq identity: |
NM_021155 |
| Classification: |
CD molecules Scavenger receptors C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000182530 |