c-Kit Antibody, ALEXA FLUOR 350

Catalog number:	bs-10005R-A350 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	c-Kit Antibody, ALEXA FLUOR 350
Quantity:	100ul
Other quantities:	100ul 332€
Related search:	kit alexa antibody gene stat receptor kinase kitlgscf

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Long name:	ALEXA FLUOR 350 Conjugated, c-Kit Polyclonal Antibody
Also known as:	Anti-c-Kit PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	c-Kit
Specificity:	This is a highly specific antibody against c-Kit
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	360-405/976
Subcellular location:	Extracellular
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-Kit
Gene ID Number:	3815
Swiss Prot:	P10721
Tested applications:	IF(ICC), IF(IHC-P)
Recommended dilutions:	IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Activated KIT also transmits signals via GRB2 and activation of RAS, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, CBL, CRK (isoform Crk-II), In response to KITLG/SCF binding, KIT can activate several signaling pathways, KIT signaling is modulated by protein phosphatases, LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, PLCG1, Phosphorylates PIK3R1, Promotes activation of STAT family members STAT1, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, SH2B2/APS and CBL, SRC and SHC1, STAT3, STAT3, STAT5A and STAT5B, STAT5A and STAT5B, and by rapid internalization and degradation of the receptor, and in melanogenesis, and of the transcription factors STAT1, gametogenesis, hematopoiesis, mast cell development, migration and function, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	CD117 SCFR C-Kit KIT
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	c-Kit
Short name:	c-Kit Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, c-reagent (Antibody to)
Alternative technique:	antibodies
Identity:	8631
Gene:	PBT | More about : PBT
Long gene name:	KIT proto-oncogene receptor tyrosine kinase
Synonyms gene name:	piebald trait v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Locus:	4q12
Discovery year:	1986-01-01
GenBank acession:	S67773
Entrez gene record:	3815
Pubmed identfication:	9027509
RefSeq identity:	NM_000222
Classification:	CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT:	OTTHUMG00000128713
Locus Specific Databases:	LRG_307

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