| Long name: |
Biotin Conjugated, NKG2D Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NKG2D |
| Specificity: |
This is a highly specific antibody against NKG2D |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
130-170/215 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from rat NKG2D |
| Gene ID number: |
24934 |
| Swiss Prot: |
O70215 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation, Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins, May play a regulatory role in differentiation and survival of NK cells, Participates in NK cell-mediated bone marrow graft rejection, Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, Signaling involves calcium influx, Stimulates perforin-mediated elimination of ligand-expressing tumor cells, culminating in the expression of TNF-alpha, leading to cytotoxic activity, Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
NKG2D KLR NKG2-D CD314 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NKG2D Conjugated |
| Short name: |
Conjugated, NKG2D Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NKG2D (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18788 |
| Gene: |
KLRK1 |
More about : KLRK1 |
| Long gene name: |
killer cell lectin like receptor K1 |
| Synonyms gene: |
D12S2489E |
| Synonyms gene name: |
DNA segment on chromosome 12 (unique) 2489 expressed sequence killer cell lectin-like receptor subfamily K, member 1 |
| Locus: |
12p13, 2 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AJ001687 |
| Entrez gene record: |
22914 |
| Pubmed identfication: |
9683661 2007850 |
| RefSeq identity: |
NM_007360 |
| Classification: |
Killer cell lectin like receptors CD molecules C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168574 |