| Long name: |
ALEXA FLUOR 350 Conjugated, BAD (Ser128) Polyclonal Antibody |
| Also known as: |
Anti-BAD Ser128 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BAD Ser128 |
| Specificity: |
This is a highly specific antibody against BAD Ser128 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser128 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-138/204 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse BAD around the phosphorylation site of Ser128 |
| Gene ID Number: |
12015 |
| Swiss Prot: |
Q61337 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Appears to act as a link between growth factor receptor signaling and the apoptotic pathways, Bcl-2 and Bcl-W, Can reverse the death repressor activity of Bcl-X(L), Successfully competes for the binding to Bcl-X(L), but not that of Bcl-2, thereby affecting the level of heterodimerization of these proteins with BAX, Promotes cell death |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
BCL2L8 BBC2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
BAD (Ser128) |
| Short name: |
BAD (Ser128) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, BCL2-associated a this GO nist on cell death (Ser128) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BAD and IDBG-53423 and ENSG00000002330 and 572, BBC2 and BCL2L8, BT, Bad and IDBG-137335 and ENSMUSG00000024959 and 12015, Cytoplasm, protein heterodimerization activity, this GO :0001666 and response to hypoxia and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006007 and glucose catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008283 and cell proliferation and biological process this GO :0008289 and lipid binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0009725 and response to hormone and biological process this GO :0009749 and response to glucose and biological process this GO :0010033 and response to organic substance and biological process this GO :0010508 and positive regulation of autophagy and biological process this GO :0010918 and positive regulation of mitochondrial membrane potential and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019050 and suppression by virus of host apoptotic process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0030346 and protein phosphatase 2B binding and molecular function this GO :0032024 and positive regulation of insulin secretion and biological process this GO :0032355 and response to estradiol and biological process this GO :0032570 and response to progesterone and biological process this GO :0033133 and positive regulation of glucokinase activity and biological process this GO :0033574 and response to testosterone and biological process this GO :0034201 and response to oleic acid and biological process this GO :0035774 and positive regulation of insulin secretion involved in cellular response to glucose stimulus and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043200 and response to amino acid and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043422 and protein kinase B binding and molecular function this GO :0044342 and type B pancreatic cell proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0046031 and ADP metabolic process and biological process this GO :0046034 and ATP metabolic process and biological process this GO :0046902 and regulation of mitochondrial membrane permeability and biological process this GO :0046931 and pore complex assembly and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051592 and response to calcium ion and biological process this GO :0060139 and positive regulation of apoptotic process by virus and biological process this GO :0060154 and cellular process regulating host cell cycle in response to virus and biological process this GO :0071247 and cellular response to chromate and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071316 and cellular response to nicotine and biological process this GO :0071396 and cellular response to lipid and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :2000078 and positive regulation of type B pancreatic cell development and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005543 : phospholipid binding and also this GO :0008289 : lipid binding and also this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030346 : protein phosphatase 2B binding and also this GO :0043422 : protein kinase B binding and also this GO :0046982 : protein heterodimerization activity, this GO :0005543 : phospholipid binding, this GO :0008289 : lipid binding, this GO :0008656 : cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030346 : protein phosphatase 2B binding, this GO :0043422 : protein kinase B binding, this GO :0046982 : protein heterodimerization activity, 55802 and IDBG-643918 and ENSBTAG00000012511 and 615013, BCL2-associated a this GO nist of cell death |
| Identity: |
936 |
| Gene: |
BAD |
More about : BAD |
| Long gene name: |
BCL2 associated agonist of cell death |
| Locus: |
11q13, 1 |
| Discovery year: |
1997-10-16 |
| GenBank acession: |
AF021792 |
| Entrez gene record: |
572 |
| Pubmed identfication: |
8929532 |
| RefSeq identity: |
NM_032989 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000134302 |