| Catalog number: | bs-0801R-Cy5 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | ARIP2B Antibody, Cy5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5 Conjugated, ARIP2B Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ARIP2B |
| Specificity: | This is a highly specific antibody against ARIP2B |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 300-350/512 |
| Subcellular location: | Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from rat ARIP2B |
| Gene ID number: | 25366 |
| Swiss Prot: | P38445 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Rat, Mouse |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | ACVR1B or ACVR1c), Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase, Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary, Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor (By similarity), FSH production by the pituitary gland, Inhibitory SMAD7, Once activated, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4, Soon after their association with the activin receptor and subsequent phosphorylation, The activated receptor type-2 then phosphorylates and activates the type-1 receptor, The type-1 receptors like ACVR1B act as downstream transducers of activin signals, This SMAD complex translocates into the nucleus where it mediates activin-induced transcription, Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, Within the receptor complex, activin-B/INHBB as well as inhibin-A/INHA-INHBA), can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, extracellular matrix production, hair follicle development and cycling, immunosuppression and carcinogenesis, on serine residues of the C-terminal tail, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, thereby blocking the activin signal, which is recruited to ACVR1B through FKBP1A, wound healing, Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1 |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 625, 650nm/670nm |
| Synonyms: | ACTR-IIB, Activin receptor type IIB, Actriib, Acvr2b, Activin receptor type-2B |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | ARIP2B Conjugated |
| Short name: | Conjugated, ARIP2B Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy5 |
| Alternative name: | cyanine 5 coupled, ARIP2B (Antibody to) |
| Alternative technique: | antibodies |
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