| Vial description: |
SIR2-like protein 1, SIR2L1, SIR2alpha, sirtuin 1, sirtuin type 1, sirtuin-1, SIRT-1 |
| Category: |
antigen |
| Raised in: |
laboratory |
| Clone: |
1 vial |
| Form: |
Purified |
| Reactivity: |
not determined |
| Purity: |
>, 90% |
| Molecular weight: |
31, 6 kDa |
| Source: |
coli, E |
| Activity: |
to be determined |
| Range: |
broad |
| Protein number: |
Q96EB6 |
| Application: |
not determined |
| Storage: |
Avoid freeze/thaw cycles, Upon delivery aliquot and store at -20°, C, C for one year, Shipped at 4° |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by acr they should be stored frozen at - 24° |
| Conjugation: |
histidine |
| Gene target: |
His-tag), SIRT1 (254-495 |
| Short name: |
His-tag) Antibody, anti-SIRT1 (254-495 |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Label: |
His |
| Alternative name: |
histidine-detection labelled) (Antibody to), antibody to-sirtuin 1 (254-495 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006364 and rRNA processing and biological process this GO :0006476 and protein deacetylation and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007346 and regulation of mitotic cell cycle and biological process this GO :0007517 and muscle organ development and biological process this GO :0007569 and cell aging and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010906 and regulation of glucose metabolic process and biological process this GO :0016032 and viral process and biological process this GO :0016239 and positive regulation of macroautophagy and biological process this GO :0016567 and protein ubiquitination and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016605 and PML body and cellular component this GO :0017136 and NAD-dependent histone deacetylase activity and molecular function this GO :0018394 and peptidyl-lysine acetylation and biological process this GO :0019213 and deacetylase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031393 and negative regulation of prostaglandin biosynthetic process and biological process this GO :0031648 and protein destabilization and biological process this GO :0031667 and response to nutrient levels and biological process this GO :0031937 and positive regulation of chromatin silencing and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0032071 and regulation of endodeoxyribonuclease activity and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032868 and response to insulin and biological process this GO :0033158 and regulation of protein import into nucleus, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0050872 and white fat cell differentiation and biological process this GO :0051019 and mitogen-activated protein kinase binding and molecular function this GO :0051097 and negative regulation of helicase activity and biological process this GO :0051574 and positive regulation of histone H3-K9 methylation and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0055089 and fatty acid homeostasis and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070403 and NAD+ binding and molecular function this GO :0070857 and regulation of bile acid biosynthetic process and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1902166 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process this GO :1990254 and keratin filament binding and molecular function this GO :2000111 and positive regulation of macrophage apoptotic process and biological process this GO :2000480 and negative regulation of cAMP-dependent protein kinase activity and biological process this GO :2000481 and positive regulation of cAMP-dependent protein kinase activity and biological process this GO :2000655 and negative regulation of cellular response to testosterone stimulus and biological process this GO :2000757 and negative regulation of peptidyl-lysine acetylation and biological process this GO :2000773 and negative regulation of cellular senescence and biological process this GO :2000774 and positive regulation of cellular senescence and biological process, SIR2L1, SIRT1 and IDBG-629119 and ENSBTAG00000014023 and 613629, SIRT1 and IDBG-75847 and ENSG00000096717 and 23411, Sirt1 and IDBG-159441 and ENSMUSG00000020063 and 93759, keratin filament binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0045087 and innate immune response and biological process this GO :0045348 and positive regulation of MHC class II biosynthetic process and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045739 and positive regulation of DNA repair and biological process this GO :0045892 and negative regulation of transcription, this GO :0000012 and single strand break repair and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000183 and chromatin silencing at rDNA and biological process this GO :0000720 and pyrimidine dimer repair by nucleotide-excision repair and biological process this GO :0000731 and DNA synthesis involved in DNA repair and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0001525 and angiogenesis and biological process this GO :0001542 and ovulation from ovarian follicle and biological process this GO :0001678 and cellular glucose homeostasis and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002039 and p53 binding and molecular function this GO :0002821 and positive regulation of adaptive immune response and biological process this GO :0003714 and transcription corepressor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005637 and nuclear inner membrane and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005677 and chromatin silencing complex and cellular component this GO :0005719 and nuclear euchromatin and cellular component this GO :0005720 and nuclear heterochromatin and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006325 and chromatin organization and biological process this GO :0006342 and chromatin silencing and biological process this GO :0006343 and establishment of chromatin silencing and biological process this GO :0006344 and maintenance of chromatin silencing and biological process this GO :0006346 and methylation-dependent chromatin silencing and biological process this GO :0006351 and transcription, this GO :0002039 : p53 binding, this GO :0002039 : p53 binding and also this GO :0003714 : transcription corepressor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0008134 : transcription factor binding and also this GO :0017136 : NAD-dependent histone deacetylase activity and also this GO :0019213 : deacetylase activity and also this GO :0019899 : enzyme binding and also this GO :0033558 : protein deacetylase activity and also this GO :0034979 : NAD-dependent protein deacetylase activity and also this GO :0042393 : histone binding and also this GO :0042802 : identical protein binding and also this GO :0043398 : HLH domain binding and also this GO :0043425 : bHLH transcription factor binding and also this GO :0046872 : metal ion binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0051019 : mitogen-activated protein kinase binding and also this GO :0070403 : NAD+ binding and also this GO :1990254 : keratin filament binding, this GO :0003714 : transcription corepressor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0008134 : transcription factor binding, this GO :0017136 : NAD-dependent histone deacetylase activity, this GO :0019213 : deacetylase activity, this GO :0019899 : enzyme binding, this GO :0033558 : protein deacetylase activity, this GO :0034979 : NAD-dependent protein deacetylase activity, this GO :0042393 : histone binding, this GO :0042802 : identical protein binding, this GO :0043398 : HLH domain binding, this GO :0043425 : bHLH transcription factor binding, this GO :0046872 : metal ion binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0051019 : mitogen-activated protein kinase binding, this GO :0070403 : NAD+ binding, this GO :1990254 : keratin filament binding, translocation and biological process this GO :0033553 and rDNA heterochromatin and cellular component this GO :0033558 and protein deacetylase activity and molecular function this GO :0034391 and regulation of smooth muscle cell apoptotic process and biological process this GO :0034979 and NAD-dependent protein deacetylase activity and molecular function this GO :0034983 and peptidyl-lysine deacetylation and biological process this GO :0035098 and ESC/E(Z) complex and cellular component this GO :0035356 and cellular triglyceride homeostasis and biological process this GO :0035358 and regulation of peroxisome proliferator activated receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0042393 and histone binding and molecular function this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043161 and proteasome-mediated ubiquitin-dependent protein catabolic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043398 and HLH domain binding and molecular function this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043518 and negative regulation of DNA damage response, sirtuin 1 |
| Identity: |
14929 |
| Gene: |
SIRT1 |
More about : SIRT1 |
| Long gene name: |
sirtuin 1 |
| Synonyms gene name: |
S, cerevisiae, cerevisiae) , homolog) 1 sirtuin (silent mating type information regulation 2 homolog) 1 (S, sirtuin (silent mating type information regulation 2 |
| Synonyms: |
SIR2L1 |
| Locus: |
10q21, 3 |
| Discovery year: |
2001-03-20 |
| GenBank acession: |
AF083106 |
| Entrez gene record: |
23411 |
| Pubmed identfication: |
10381378 |
| RefSeq identity: |
NM_012238 |
| Classification: |
Sirtuins |
| Havana BLAST/BLAT: |
OTTHUMG00000018340 |