| Long name: |
SPAG5 Primary Polyclonal Antibody |
| Also known as: |
SPAG5 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SPAG5 |
| Specificity: |
This is a highly specific antibody against SPAG5 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1120-1170/1193 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SPAG5/MAP126 |
| Gene ID number: |
10615 |
| Swiss Prot: |
Q96R06 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
In complex with SKAP, In non-mitotic cells, May contribute to the regulation of separase activity, May enhance GSK3B-mediated phosphorylation of other substrates, May regulate AURKA localization to mitotic spindle, Required for chromosome alignment, and maintenance of spindle pole architecture, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), normal timing of sister chromatid segregation, promotes stable microtubule-kinetochore attachments, such as MAPT/TAU, thereby preventing mTORC1 hyperactivation-induced apoptosis, upon stress induction, Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Astrin, DEEPEST, Mitotic spindle-associated protein p126, SPAG5, Sperm-associated antigen 5, hMAP126, MAP126 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SPAG5 |
| Short name: |
SPAG5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SPAG5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13452 |
| Gene: |
SPAG5 |
More about : SPAG5 |
| Long gene name: |
sperm associated antigen 5 |
| Synonyms: |
DEEPEST MAP126 hMAP126 |
| Synonyms name: |
mitotic spindle coiled-coil related protein astrin mitotic spindle associated protein p126 |
| Locus: |
17q11, 2 |
| Discovery year: |
2002-10-08 |
| GenBank acession: |
AF063308 |
| Entrez gene record: |
10615 |
| Pubmed identfication: |
11549262 |
| RefSeq identity: |
NM_006461 |
| Havana BLAST/BLAT: |
OTTHUMG00000166586 |