c-Kit Antibody, Cy7 Conjugated

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Catalog number: bs-0672R-Cy7
Price: 350 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: c-Kit Antibody, Cy7 Conjugated
Quantity: 0.1ml
Other quantities: 0.1ml 350€
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More details :

Long name: Cy7 Conjugated, c-Kit Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Cy7
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: c-Kit
Specificity: This is a highly specific antibody against c-Kit
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 928-964/988
Subcellular location: Cytoplasm
Source: KLH conjugated synthetic peptide derived from human CD117/c-kit
Gene ID number: 3815
Swiss Prot: P10721
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Dog, Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Activated KIT also transmits signals via GRB2 and activation of RAS, Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1, CBL, CRK (isoform Crk-II), In response to KITLG/SCF binding, KIT can activate several signaling pathways, KIT signaling is modulated by protein phosphatases, LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, PLCG1, Phosphorylates PIK3R1, Promotes activation of STAT family members STAT1, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, SH2B2/APS and CBL, SRC and SHC1, STAT3, STAT3, STAT5A and STAT5B, STAT5A and STAT5B, and by rapid internalization and degradation of the receptor, and in melanogenesis, and of the transcription factors STAT1, gametogenesis, hematopoiesis, mast cell development, migration and function, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 743nm/767nm
Synonyms: C-Kit, CD117, KIT, Mast/stem cell growth factor receptor Kit, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PBT
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated: These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target: c-Kit Conjugated
Short name: Conjugated, c-Kit Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Cy7
Alternative name: cyanine 7 coupled, c-reagent (Antibody to)
Alternative technique: antibodies

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