| Long name: |
FITC Conjugated, GHR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GHR |
| Specificity: |
This is a highly specific antibody against GHR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
290-340/638 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human GHR |
| Gene ID number: |
2690 |
| Swiss Prot: |
P10912 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Pig, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling, On ligand binding, The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling, couples to the JAK2/STAT5 pathway (By similarity), Receptor for pituitary gland growth hormone involved in regulating postnatal body growth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GHBP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GHR Conjugated |
| Short name: |
FITC Conjugated, GHR Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, growth hormone receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GHBP, GHR and IDBG-18930 and ENSG00000112964 and 2690, GHR and IDBG-629685 and ENSBTAG00000001335 and 280805, Ghr and IDBG-127871 and ENSMUSG00000055737 and 14600, nuclei, proline-rich region binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0000255 and allantoin metabolic process and biological process this GO :0004903 and growth hormone receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006101 and citrate metabolic process and biological process this GO :0006103 and 2-oxoglutarate metabolic process and biological process this GO :0006105 and succinate metabolic process and biological process this GO :0006107 and oxaloacetate metabolic process and biological process this GO :0006549 and isoleucine metabolic process and biological process this GO :0006573 and valine metabolic process and biological process this GO :0006600 and creatine metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009725 and response to hormone and biological process this GO :0009755 and hormone-mediated signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019530 and taurine metabolic process and biological process this GO :0019838 and growth factor binding and molecular function this GO :0019898 and extrinsic component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0032094 and response to food and biological process this GO :0032355 and response to estradiol and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042976 and activation of Janus kinase activity and biological process this GO :0042977 and activation of JAK2 kinase activity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043278 and response to morphine and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0044236 and multicellular organismal metabolic process and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046427 and positive regulation of JAK-STAT cascade and biological process this GO :0046449 and creatinine metabolic process and biological process this GO :0046898 and response to cycloheximide and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0060396 and growth hormone receptor signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070064 and proline-rich region binding and molecular function this GO :0070195 and growth hormone receptor complex and cellular component this GO :0070555 and response to interleukin-1 and biological process this GO :1901215 and negative regulation of neuron death and biological process, this GO :0004903 : growth hormone receptor activity, this GO :0004903 : growth hormone receptor activity and also this GO :0005515 : protein binding and also this GO :0017046 : peptide hormone binding and also this GO :0019838 : growth factor binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0042169 : SH2 domain binding and also this GO :0042803 : protein homodimerization activity and also this GO :0070064 : proline-rich region binding, this GO :0005515 : protein binding, this GO :0017046 : peptide hormone binding, this GO :0019838 : growth factor binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0042169 : SH2 domain binding, this GO :0042803 : protein homodimerization activity, this GO :0070064 : proline-rich region binding, growth hormone receptor |
| Identity: |
4263 |
| Gene: |
GHR |
More about : GHR |
| Long gene name: |
growth hormone receptor |
| Synonyms name: |
growth hormone binding protein |
| Locus: |
5p13, 1-p12 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
2690 |
| RefSeq identity: |
NM_000163 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000094791 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |