| Long name: |
ALEXA FLUOR 488 Conjugated, DVL1 Polyclonal Antibody |
| Also known as: |
Anti-DVL1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DVL1 |
| Specificity: |
This is a highly specific antibody against DVL1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
20-70/695 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DVL1 |
| Gene ID Number: |
1855 |
| Swiss Prot: |
O14640 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ), Plays a role both in canonical and non-canonical Wnt signaling, Plays a role in the signal transduction pathways mediated by multiple Wnt genes, Required for LEF1 activation upon WNT1 and WNT3A signaling, Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DVL1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DVL1 |
| Short name: |
DVL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, DVL1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3084 |
| Gene: |
DVL1 |
More about : DVL1 |
| Long gene name: |
dishevelled segment polarity protein 1 |
| Synonyms gene name: |
dishevelled 1 (homologous to Drosophila dsh) dishevelled, dsh homolog 1 (Drosophila) |
| Locus: |
1p36, 33 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
AF006011 |
| Entrez gene record: |
1855 |
| Pubmed identfication: |
8817329 |
| RefSeq identity: |
NM_004421 |
| Classification: |
Dishevelled segment polarity proteins PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000003069 |