| Catalog number: | bs-0591R |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | DR4 Antibody |
| Quantity: | 0.1ml |
| Other quantities: | 1 tube 532€ 1 x 1 vial 591€ |
| Related search: |
| Long name: | DR4 Primary Polyclonal Antibody |
|---|---|
| Also known as: | DR4 PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | DR4 |
| Specificity: | This is a highly specific antibody against DR4 |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 420-468/468 |
| Subcellular location: | Cytoplasm |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR4 |
| Gene ID number: | 8797 |
| Swiss Prot: | O00220 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Promotes the activation of NF-kappa-B, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, Receptor for the cytotoxic ligand TNFSF10/TRAIL |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | APO2, CD261, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, TRAILR-1, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, DR4 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | DR4 |
| Short name: | DR4 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | DR4 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 11904 |
| Gene: | TNFRSF10A | More about : TNFRSF10A |
| Long gene name: | TNF receptor superfamily member 10a |
| Synonyms gene name: | member 10a , tumor necrosis factor receptor superfamily |
| Synonyms: | DR4 Apo2 TRAILR-1 CD261 |
| Locus: | 8p21, 3 |
| Discovery year: | 1998-12-04 |
| GenBank acession: | U90875 |
| Entrez gene record: | 8797 |
| Pubmed identfication: | 9311998 9082980 |
| RefSeq identity: | NM_003844 |
| Classification: | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: | OTTHUMG00000097843 |
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| bs-0591R-Cy3 | DR4 Antibody, Cy3 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-0591R-Cy5 | DR4 Antibody, Cy5 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
| bs-0591R-Cy5.5 | DR4 Antibody, Cy5.5 Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
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