| Long name: |
VWF Primary Polyclonal Antibody |
| Also known as: |
VWF PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
VWF |
| Specificity: |
This is a highly specific antibody against VWF |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
730-780/2813 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human VWF |
| Gene ID number: |
7450 |
| Swiss Prot: |
P04275 |
| Tested Applications: |
IF(ICC), IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma, Important in the maintenance of hemostasis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
F8VWF, vWF, von Willebrand factor, VWD |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VWF |
| Short name: |
VWF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
von Willebrand factor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, F8VWF and VWD, VWF and IDBG-13506 and ENSG00000110799 and 7450, VWF and IDBG-640531 and ENSBTAG00000012265 and 280958, Vwf and IDBG-189967 and ENSMUSG00000001930 and 22371, chaperone binding, intrinsic pathway and biological process this GO :0007599 and hemostasis and biological process this GO :0009611 and response to wounding and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0019865 and immunoglobulin binding and molecular function this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0031091 and platelet alpha granule and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0031589 and cell-substrate adhesion and biological process this GO :0033093 and Weibel-Palade body and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0051260 and protein homooli this GO merization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001889 and liver development and biological process this GO :0001890 and placenta development and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0002020 and protease binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0007597 and blood coagulation, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0002020 : protease binding and also this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0019865 : immunoglobulin binding and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0047485 : protein N-terminus binding and also this GO :0051087 : chaperone binding, this GO :0002020 : protease binding, this GO :0005178 : integrin binding, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0019865 : immunoglobulin binding, this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0047485 : protein N-terminus binding, this GO :0051087 : chaperone binding, von Willebrand factor |
| Identity: |
12726 |
| Gene: |
VWF |
More about : VWF |
| Long gene name: |
von Willebrand factor |
| Synonyms gene: |
F8VWF |
| Locus: |
12p13, 31 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
7450 |
| Pubmed identfication: |
2251280 |
| RefSeq identity: |
NM_000552 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000168265 |
| Locus Specific Databases: |
Von Willebrand Factor Database LRG_587 |