| Long name: |
Recombinant Human ERBB3 Protein |
| Type: |
Recombinant protein |
| Knowledgebase of uniprot: |
Arg1- Leu131 (P21860) |
| Gene name synonym: |
ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 |
| Purification: |
Greater than 95% (SDS-PAGE analysis) |
| Examined analyses: |
Antigen, ELISA, SDS-PAGE, Western blotting |
| Expressed in: |
Escherichia coli |
| KiloDaltons of the protein: |
15kDa |
| Storage conditions: |
For long termstorage, The cycles of freezing and thawing are not recommended as such cycles can damage the structure of the polypeptide chains, freeze and keep at -20°, please, C, C for up to one month, Human ERBB3 Protein can be refrigerated at +4° |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
ERBB3 Protein |
| Short name: |
ERBB3 Protein |
| Species: |
Humans, Human |
| Alternative name: |
sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) Protein, H |
| Alternative to gene target: |
ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, Extracellular, c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, this GO :0003197 and endocardial cushion development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0014037 and Schwann cell differentiation and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004716 : receptor signaling protein tyrosine kinase activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004716 : receptor signaling protein tyrosine kinase activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019838 : growth factor binding, this GO :0030296 : protein tyrosine kinase activator activity, this GO :0042803 : protein homodimerization activity, this GO :0046982 : protein heterodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838 : growth factor binding and also this GO :0030296 : protein tyrosine kinase activator activity and also this GO :0042803 : protein homodimerization activity and also this GO :0046982 : protein heterodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0021545 and cranial nerve development and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042060 and wound healing and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051048 and negative regulation of secretion and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
| Identity: |
3431 |
| Gene: |
ERBB3 |
More about : ERBB3 |
| Long gene name: |
erb-b2 receptor tyrosine kinase 3 |
| Synonyms gene: |
LCCS2 |
| Synonyms gene name: |
lethal congenital contracture syndrome 2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
| Synonyms: |
HER3 |
| Synonyms name: |
human epidermal growth factor receptor 3 |
| Locus: |
12q13, 2 |
| Discovery year: |
1990-07-15 |
| GenBank acession: |
M34309 |
| Entrez gene record: |
2065 |
| RefSeq identity: |
NM_001982 |
| Classification: |
Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000170140 |
| Locus Specific Databases: |
LRG_996 |