| Long name: |
ALEXA FLUOR 594 Conjugated, SCF Polyclonal Antibody |
| Also known as: |
Anti-SCF PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SCF |
| Specificity: |
This is a highly specific antibody against SCF |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
160-210/273 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCF |
| Gene ID Number: |
4254 |
| Swiss Prot: |
P21583 |
| Tested applications: |
IF(IHC-F), IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
KITLG/SCF acts synergistically with other cytokines, KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, KITLG/SCF and KIT promote activation of PLCG1, KITLG/SCF and KIT promote activation of STAT family members STAT1, KITLG/SCF binding can activate several signaling pathways, Plays an essential role in the regulation of cell survival and proliferation, Promotes phosphorylation of PIK3R1, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1, STAT3 and STAT5, and in melanogenesis, and subsequent activation of the kinase AKT1, gametogenesis, hematopoiesis, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, mast cell development, migration and function, probably interleukins, stem cell maintenance, the regulatory subunit of phosphatidylinositol 3-kinase, 4, 5-trisphosphate, Ligand for the receptor-type protein-tyrosine kinase KIT |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
SCF SF Kitl KL-1 FPH2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
SCF |
| Short name: |
SCF Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, SCF (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6343 |
| Gene: |
KITLG |
More about : KITLG |
| Long gene name: |
KIT ligand |
| Synonyms gene: |
MGF |
| Synonyms name: |
mast cell growth factor stem cell factor steel factor familial progressive hyperpigmentation 2 |
| Locus: |
12q21, 32 |
| Discovery year: |
1991-06-04 |
| GenBank acession: |
M59964 |
| Entrez gene record: |
4254 |
| Pubmed identfication: |
2208279 1707188 19375057 |
| RefSeq identity: |
NM_003994 |
| Havana BLAST/BLAT: |
OTTHUMG00000169888 |