| Catalog number: | bs-0518R-Cy5.5 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | ATF2 Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, ATF2 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ATF2 |
| Specificity: | This is a highly specific antibody against ATF2 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 415-455/505 |
| Subcellular location: | Mitochondrion, Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human ATF2 |
| Gene ID number: | 1386 |
| Swiss Prot: | P15336 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type, Dependent on its binding partner, Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro, In concert with CUL3 and RBX1, In the cytoplasm, In the nucleus, The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF), and DNA damage response, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'), cell growth, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, including those involved in anti-apoptosis, inducing mitochondrial leakage and promoting cell death, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, proliferation and death, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM, thereby impairing mitochondrial membrane potential, Transcriptional activator which regulates the transcription of various genes |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Synonyms: | ATF1 ATF2 HFB1-GDNF |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | ATF2 Conjugated |
| Short name: | Conjugated, ATF2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, ATF2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4232 |
| Gene: | GDNF | More about : GDNF |
| Long gene name: | glial cell derived neurotrophic factor |
| Synonyms name: | astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor |
| Locus: | 5p13, 2 |
| Discovery year: | 1995-05-04 |
| Entrez gene record: | 2668 |
| Pubmed identfication: | 8493557 |
| RefSeq identity: | NM_000514 |
| Classification: | Endogenous ligands |
| Havana BLAST/BLAT: | OTTHUMG00000090809 |
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| bs-5169R-Cy3 | ATF2 (Ser322) Antibody, Cy3 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-5169R-Cy5 | ATF2 (Ser322) Antibody, Cy5 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-5169R-Cy7 | ATF2 (Ser322) Antibody, Cy7 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-5169R-FITC | ATF2 (Ser322) Antibody, FITC Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
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| bs-5170R-Biotin | ATF2 (Ser44) Antibody, Biotin Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
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