| Long name: |
Biotin Conjugated, CD18 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD18 |
| Specificity: |
This is a highly specific antibody against CD18 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
724-769/769 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human Integrin beta 2 |
| Gene ID number: |
3689 |
| Swiss Prot: |
P05107 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ICAM2, ICAM3 and ICAM4, Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1, Integrin alpha-M/beta-2 is also a receptor for factor X, Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain, Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen, Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation, Integrin alpha-L/beta-2 is a receptor for ICAM1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LFA-1 MAC-1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD18 Conjugated |
| Short name: |
Conjugated, CD18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CD18 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6155 |
| Gene: |
ITGB2 |
More about : ITGB2 |
| Long gene name: |
integrin subunit beta 2 |
| Synonyms gene: |
CD18 MFI7 |
| Synonyms gene name: |
beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms name: |
complement component 3 receptor 3 and 4 subunit |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK222505 |
| Entrez gene record: |
3689 |
| RefSeq identity: |
NM_000211 |
| Classification: |
Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000090257 |
| Locus Specific Databases: |
ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |