| Long name: |
ALEXA FLUOR 488 Conjugated, CD18 Polyclonal Antibody |
| Also known as: |
Anti-CD18 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD18 |
| Specificity: |
This is a highly specific antibody against CD18 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
724-769/769 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 2 |
| Gene ID Number: |
3689 |
| Swiss Prot: |
P05107 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ICAM2, ICAM3 and ICAM4, Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1, Integrin alpha-M/beta-2 is also a receptor for factor X, Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain, Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain, Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen, Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation, Integrin alpha-L/beta-2 is a receptor for ICAM1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
LFA-1 MAC-1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CD18 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CD18 |
| Short name: |
CD18 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CD18 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6155 |
| Gene: |
ITGB2 |
More about : ITGB2 |
| Long gene name: |
integrin subunit beta 2 |
| Synonyms gene: |
CD18 MFI7 |
| Synonyms gene name: |
beta 2 (antigen CD18 (p95), beta 2 (complement component 3 receptor 3 and 4 subunit) , integrin, lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit) integrin |
| Synonyms name: |
complement component 3 receptor 3 and 4 subunit |
| Locus: |
21q22, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AK222505 |
| Entrez gene record: |
3689 |
| RefSeq identity: |
NM_000211 |
| Classification: |
Complement system Integrin beta subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000090257 |
| Locus Specific Databases: |
ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I) LRG_76 |