| Long name: |
FITC Conjugated, RGS2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RGS2 |
| Specificity: |
This is a highly specific antibody against RGS2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Cell membrane, Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human RGS2 |
| Gene ID number: |
5997 |
| Swiss Prot: |
P41220 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds EIF2B5 and blocks its activity, May play a role in leukemogenesis, Plays a role in negative feedback control pathway for adenylyl cyclase signaling, thereby inhibiting the translation of mRNA into protein, Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RGS2 Conjugated |
| Short name: |
FITC Conjugated, RGS2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
24kDa (Antibody to), fluorecein coupled, regulator on G-protein signaling 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
24kDa, G0S8, RGS2 and IDBG-105451 and ENSG00000116741 and 5997, RGS2 and IDBG-629676 and ENSBTAG00000034366 and 100848920, Rgs2 and IDBG-197102 and ENSMUSG00000026360 and 19735, beta-tubulin binding, nuclei, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006417 and regulation of translation and biological process this GO :0007049 and cell cycle and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008277 and regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0010519 and negative regulation of phospholipase activity and biological process this GO :0010614 and negative regulation of cardiac muscle hypertrophy and biological process this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0038032 and termination of G-protein coupled receptor signaling pathway and biological process this GO :0043005 and neuron projection and cellular component this GO :0043407 and negative regulation of MAP kinase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0043951 and negative regulation of cAMP-mediated signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0048487 and beta-tubulin binding and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0055119 and relaxation of cardiac muscle and biological process this GO :0060087 and relaxation of vascular smooth muscle and biological process this GO :0060452 and positive regulation of cardiac muscle contraction and biological process this GO :0071877 and regulation of adrenergic receptor signaling pathway and biological process, this GO :0005096 : GTPase activator activity, this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0048487 : beta-tubulin binding, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0048487 : beta-tubulin binding, 513055, regulator of G-protein signaling 2 |
| Identity: |
9998 |
| Gene: |
RGS2 |
More about : RGS2 |
| Long gene name: |
regulator of G-protein signaling 2 |
| Synonyms gene: |
G0S8 |
| Synonyms gene name: |
24kD regulator of G-protein signalling 2, 24kDa , 24kDa regulator of G-protein signaling 2, regulator of G-protein signalling 2 |
| Locus: |
1q31, 2 |
| Discovery year: |
1994-11-01 |
| GenBank acession: |
L13463 |
| Entrez gene record: |
5997 |
| Pubmed identfication: |
8179820 |
| RefSeq identity: |
NM_002923 |
| Classification: |
Endogenous ligands Regulators of G-protein signaling |
| Havana BLAST/BLAT: |
OTTHUMG00000035600 |