| Long name: |
ALEXA FLUOR 647 Conjugated, PPP4C Polyclonal Antibody |
| Also known as: |
Anti-PPP4C PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PPP4C |
| Specificity: |
This is a highly specific antibody against PPP4C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
260-307/307 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PP4C |
| Gene ID Number: |
5531 |
| Swiss Prot: |
P60510 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
DNA damage checkpoint signaling, DNA repair, Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity), In response to DNA damage, NF-kappa-B activation and cell migration, The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3, The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-14 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair, activation of c-Jun N-terminal kinase MAPK8, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin, apoptosis, catalyzes RPA2 dephosphorylation, maturation of spliceosomal snRNPs, regulation of histone acetylation, tumor necrosis factor (TNF)-alpha signaling, Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PP4 PPX |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the PPP4C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
PPP4C |
| Short name: |
PPP4C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, PPP4C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9319 |
| Gene: |
PPP4C |
More about : PPP4C |
| Long gene name: |
protein phosphatase 4 catalytic subunit |
| Synonyms gene name: |
catalytic subunit , catalytic subunit protein phosphatase 4, protein phosphatase 4 (formerly X) |
| Synonyms name: |
catalytic subunit , protein phosphatase X |
| Locus: |
16p11, 2 |
| Discovery year: |
1993-01-22 |
| Entrez gene record: |
5531 |
| Pubmed identfication: |
9177794 |
| RefSeq identity: |
NM_002720 |
| Classification: |
Protein phosphatase catalytic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000132113 |