| Long name: |
Cy7 Conjugated, EphA2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EphA2 |
| Specificity: |
This is a highly specific antibody against EphA2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
920-970/976 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human EphA2 |
| Gene ID number: |
1969 |
| Swiss Prot: |
P29317 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activated by the ligand ephrin-A1/EFNA1 regulates migration, During development, Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance, Involved for instance in angiogenesis, May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration, Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development, integrin-mediated adhesion, leading to contact-dependent bidirectional signaling into neighboring cells, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues, proliferation and differentiation of cells, respectively) signaling pathway, Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
ARCC2, CTPA, CTPP1, CTRCT6, EPHA2, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, ECK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
EphA2 Conjugated |
| Short name: |
Conjugated, EphA2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, EPH receptor A2 (Antibody to) |
| Alternative technique: |
antibodies |