| Long name: |
DR3 Primary Polyclonal Antibody |
| Also known as: |
DR3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DR3 |
| Specificity: |
This is a highly specific antibody against DR3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
370-417/417 |
| Subcellular location: |
Intracellular, Cell membrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DR3 |
| Gene ID number: |
8718 |
| Swiss Prot: |
Q93038 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Interacts directly with the adapter TRADD, May play a role in regulating lymphocyte homeostasis, Mediates activation of NF-kappa-B and induces apoptosis, Receptor for TNFSF12/APO3L/TWEAK |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APO-3, APO3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, TNFRSF25, TR3, TRAMP, Tumor necrosis factor receptor superfamily member 25, UNQ455/PRO779, WSL, WSL-1, WSL-LR, WSL1, DR3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DR3 |
| Short name: |
DR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11910 |
| Gene: |
TNFRSF25 |
More about : TNFRSF25 |
| Long gene name: |
TNF receptor superfamily member 25 |
| Synonyms gene: |
TNFRSF12 |
| Synonyms gene name: |
member 12 (translocating chain-association membrane protein) tumor necrosis factor receptor superfamily, member 25 , tumor necrosis factor receptor superfamily |
| Synonyms: |
DR3 TRAMP WSL-1 LARD WSL-LR DDR3 TR3 APO-3 |
| Locus: |
1p36, 31 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
U72763 |
| Entrez gene record: |
8718 |
| Pubmed identfication: |
9052839 8934525 |
| RefSeq identity: |
NM_148965 |
| Classification: |
Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000000831 |