| Long name: |
HRP Conjugated, MMP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MMP2 |
| Specificity: |
This is a highly specific antibody against MMP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
20-70/476 |
| Subcellular location: |
Secreted |
| Source: |
MAT conjugated synthetic peptide derived from human MMP2 |
| Gene ID number: |
4313 |
| Swiss Prot: |
P08253 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also cleaves KISS at a Gly-|-Leu bond, Appears to have a role in myocardial cell death pathways, As well as degrading extracellular matrix proteins, Cleaves GSK3beta in vitro, Contributes to myocardial oxidative stress by regulating the activity of GSK3beta, Involved in the formation of the fibrovascular tissues in association with MMP14, Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, Ligand for integrinv/beta3 on the surface of blood vessels, NFAT and IRF transcriptional pathways, PEX, and atherosclerotic plaque rupture, angiogenesis, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction, inflammation, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin, the C-terminal non-catalytic fragment of MMP2, tissue repair, tumor invasion, Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
TBE-1 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
MMP2 Conjugated |
| Short name: |
Conjugated, MMP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, MMP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7166 |
| Gene: |
MMP2 |
More about : MMP2 |
| Long gene name: |
matrix metallopeptidase 2 |
| Synonyms gene: |
CLG4 CLG4A |
| Synonyms gene name: |
72kDa gelatinase, 72kDa type IV collagenase) , matrix metalloproteinase 2 (gelatinase A |
| Locus: |
16q12, 2 |
| Discovery year: |
1989-05-25 |
| Entrez gene record: |
4313 |
| Classification: |
Matrix metallopeptidases |
| Havana BLAST/BLAT: |
OTTHUMG00000133202 |