| Long name: |
ALEXA FLUOR 488 Conjugated, MBP Polyclonal Antibody |
| Also known as: |
Anti-MBP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MBP |
| Specificity: |
This is a highly specific antibody against MBP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
45-87/167 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from Guinea Pig MBP |
| Tested applications: |
IF(IHC-F), IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis, They have a role in both its formation and stabilization, and may also be involved in signaling pathways in T cells and neural cells, each of them having maybe a specialized function, maybe as components of transcriptional complexes, Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the MBP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
MBP |
| Short name: |
MBP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, MBP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6925 |
| Gene: |
MBP |
More about : MBP |
| Long gene name: |
myelin basic protein |
| Locus: |
18q23 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
4155 |
| Pubmed identfication: |
2425357 |
| RefSeq identity: |
NM_001025081 |
| Havana BLAST/BLAT: |
OTTHUMG00000132874 |