| Long name: |
Biotin Conjugated, EphB2 R Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EphB2 R |
| Specificity: |
This is a highly specific antibody against EphB2 R |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
100-150/1055 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human EphB2 R |
| Gene ID number: |
2048 |
| Swiss Prot: |
P29323 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk, Controls other aspects of development including angiogenesis, Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca, Functions in axon guidance during development, In addition to axon guidance, Involved in the guidance of commissural axons, May function as a tumor suppressor, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses, leading to contact-dependent bidirectional signaling into neighboring cells, palate development and in inner ear development through regulation of endolymph production, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CAPB, Developmentally-regulated Eph-related tyrosine kinase, EK5, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EPHB2, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, Hek5, PCBC, Renal carcinoma antigen NY-REN-47, Tyro5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3, DRT |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EphB2 R Conjugated |
| Short name: |
Conjugated, EphB2 R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, EphB2 R (Antibody to) |
| Alternative technique: |
antibodies |