| Long name: |
ALEXA FLUOR 647 Conjugated, EphB2 R Polyclonal Antibody |
| Also known as: |
Anti-EphB2 R PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EphB2 R |
| Specificity: |
This is a highly specific antibody against EphB2 R |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/1055 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EphB2 R |
| Gene ID Number: |
2048 |
| Swiss Prot: |
P29323 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk, Controls other aspects of development including angiogenesis, Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca, Functions in axon guidance during development, In addition to axon guidance, Involved in the guidance of commissural axons, May function as a tumor suppressor, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses, leading to contact-dependent bidirectional signaling into neighboring cells, palate development and in inner ear development through regulation of endolymph production, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex, Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CAPB, Developmentally-regulated Eph-related tyrosine kinase, EK5, ELK-related tyrosine kinase, EPH tyrosine kinase 3, EPH-like kinase 5, EPHB2, EPHT3, EPTH3, ERK, Ephrin type-B receptor 2, Hek5, PCBC, Renal carcinoma antigen NY-REN-47, Tyro5, Tyrosine-protein kinase TYRO5, Tyrosine-protein kinase receptor EPH-3, DRT |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the EphB2 R Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
EphB2 R |
| Short name: |
EphB2 R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, EphB2 R (Antibody to) |
| Alternative technique: |
antibodies |