| Long name: |
Biotin Conjugated, PMP22 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PMP22 |
| Specificity: |
This is a highly specific antibody against PMP22 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
117-133/160 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PMP-22 |
| Gene ID number: |
5376 |
| Swiss Prot: |
Q01453 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Alterations in the level of this protein cause several genetic human diseases, If one copy of the gene is deleted, If the protein is duplicated, In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration, patients develop Charcot Marie Tooth disease, they suffer from the inherited tendency to pressure palsies, PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PMP22 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PMP22 Conjugated |
| Short name: |
Conjugated, PMP22 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PMP22 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9716 |
| Gene: |
PXMP2 |
More about : PXMP2 |
| Long gene name: |
peroxisomal membrane protein 2 |
| Synonyms gene name: |
22kDa , peroxisomal membrane protein 2 (22kD) peroxisomal membrane protein 2 |
| Locus: |
12q24, 33 |
| Discovery year: |
1992-03-03 |
| Entrez gene record: |
5827 |
| Pubmed identfication: |
11590176 |
| RefSeq identity: |
NM_018663 |
| Havana BLAST/BLAT: |
OTTHUMG00000168019 |