| Long name: |
Cy3 Conjugated, Fas Ligand Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Fas Ligand |
| Specificity: |
This is a highly specific antibody against Fas Ligand |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
170-220/281 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Fas Ligand |
| Gene ID number: |
356 |
| Swiss Prot: |
P48023 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects, May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development, TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition, a receptor that transduces the apoptotic signal into cells, in the antigen-stimulated suicide of mature T-cells, or both, Cytokine that binds to TNFRSF6/FAS |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
ALPS1B, APT1LG1, Apoptosis antigen ligand, CD178, CD95 ligand, CD95-L, CD95L, FASL, FASLG, Fas antigen ligand, Fas ligand, TNFSF6, Tumor necrosis factor ligand superfamily member 6, APTL |
| Properties: |
1 of the Fas Ligand Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Gene target: |
Fas Ligand Conjugated |
| Short name: |
Conjugated, Fas Ligand Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, member 6) Ligand (Antibody to), Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |