| Long name: |
FITC Conjugated, GLP-2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GLP-2 |
| Specificity: |
This is a highly specific antibody against GLP-2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1-15/32 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human GLP-2 |
| Gene ID number: |
2641 |
| Swiss Prot: |
P01275 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A counterregulatory hormone of insulin, CRH, GLP-1 is a potent stimulator of glucose-dependent insulin release, GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity, Have growth-promoting activities on intestinal epithelium, Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation, Inhibits beta cell apoptosis, Inhibits gastric emptying in humans, May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, May play an important role in intestinal mucosal growth in the early period of life, Oxyntomodulin significantly reduces food intake, Play important roles on gastric motility and the suppression of plasma glucagon levels, Plays a key role in nutrient homeostasis, Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes, Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis, Stimulates intestinal glucose transport and decreases mucosal permeability, Suppression of gastric emptying may lead to increased gastric distension, TSH, The gastrointestinal tract, and vasopressin secretion, as well as increasing nutrient disposal, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis, enhancing nutrient assimilation through enhanced gastrointestinal function, from the stomach to the colon is the principal target for GLP-2 action, independent of the actions of insulin, oxytocin, raises plasma glucose levels in response to insulin-induced hypoglycemia, which may contribute to satiety by causing a sensation of fullness, Glucagon plays a key role in glucose metabolism and homeostasis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GCG, GLP 2, GRPP, Glicentin, Glicentin related polypeptide, Glucagon like peptide 2, Glucagon precursor, Glucagon preproprotein, OXM, OXY, Oxyntomodulin, glp-2, Glucagan-like petide |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GLP-2 Conjugated |
| Short name: |
FITC Conjugated, GLP-2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GLP-2 (Antibody to) |
| Alternative technique: |
antibodies |