| Catalog number: | bs-0119R |
|---|---|
| Price: | 263 € |
| Supplier: | Bioss Primary Unconjugated Antibodies |
| Product name: | c FLIP Antibody |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | c FLIP Primary Polyclonal Antibody |
|---|---|
| Also known as: | c FLIP PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | FLIP |
| Specificity: | This is a highly specific antibody against FLIP |
| Modification(s): | None |
| Modification site(s): | Unmodified antibody |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 1-50/480 |
| Subcellular location: | Intracellular |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human c-FLIP |
| Gene ID number: | 8837 |
| Swiss Prot: | O15519 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex, Acts as an inhibitor of TNFRSF6 mediated apoptosis, Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis, Lacks enzymatic (caspase) activity, Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | CASP8 and FADD-like apoptosis regulator, CASP8AP1, CFLAR, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASH |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | c FLIP |
| Short name: | c FLIP Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | c FLIP (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 1876 |
| Gene: | CFLAR | More about : CFLAR |
| Long gene name: | CASP8 and FADD like apoptosis regulator |
| Synonyms gene: | CASP8AP1 |
| Synonyms gene name: | CASP8 and FADD-like apoptosis regulator |
| Synonyms: | CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP |
| Locus: | 2q33, 1 |
| Discovery year: | 1999-05-07 |
| GenBank acession: | AF005774 |
| Entrez gene record: | 8837 |
| Pubmed identfication: | 9208847 9217161 |
| RefSeq identity: | NM_003879 |
| Classification: | Endogenous ligands Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: | OTTHUMG00000132819 |
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