| Long name: |
Cy3 Conjugated, IDE Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IDE |
| Specificity: |
This is a highly specific antibody against IDE |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
514-564/1019 |
| Subcellular location: |
Cell membrane, Secreted, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human IDE |
| Gene ID number: |
3416 |
| Swiss Prot: |
P14735 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Degrades amyloid formed by APP and IAPP, IAPP, May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia, and thereby plays a role in intercellular peptide signaling, bradykinin, glucagon, kallidin and other peptides, Plays a role in the cellular breakdown of insulin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Properties: |
1 of the IDE Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IDE Conjugated |
| Short name: |
Conjugated, IDE Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, insulin-degrading enzyme (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IDE and IDBG-637578 and ENSBTAG00000019759 and 523752, IDE and IDBG-82456 and ENSG00000119912 and 3416, INSULYSIN, Ide and IDBG-161417 and ENSMUSG00000056999 and 15925, metal ion binding, nuclei, this GO :0001540 and beta-amyloid binding and molecular function this GO :0001948 and glycoprotein binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004222 and metalloendopeptidase activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005782 and peroxisomal matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006508 and proteolysis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008340 and determination of adult lifespan and biological process this GO :0009986 and cell surface and cellular component this GO :0010815 and bradykinin catabolic process and biological process this GO :0010992 and ubiquitin homeostasis and biological process this GO :0016032 and viral process and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017046 and peptide hormone binding and molecular function this GO :0031597 and cytosolic proteasome complex and cellular component this GO :0031626 and beta-endorphin binding and molecular function this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0042277 and peptide binding and molecular function this GO :0042447 and hormone catabolic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043130 and ubiquitin binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0044257 and cellular protein catabolic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051289 and protein homotetramerization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :1901142 and insulin metabolic process and biological process this GO :1901143 and insulin catabolic process and biological process, this GO :0001540 : beta-amyloid binding, this GO :0001540 : beta-amyloid binding and also this GO :0001948 : glycoprotein binding and also this GO :0003824 : catalytic activity and also this GO :0004222 : metalloendopeptidase activity and also this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008270 : zinc ion binding and also this GO :0016887 : ATPase activity and also this GO :0017046 : peptide hormone binding and also this GO :0031626 : beta-endorphin binding and also this GO :0042277 : peptide binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043130 : ubiquitin binding and also this GO :0043559 : insulin binding and also this GO :0046872 : metal ion binding, this GO :0001948 : glycoprotein binding, this GO :0003824 : catalytic activity, this GO :0004222 : metalloendopeptidase activity, this GO :0005102 : receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008270 : zinc ion binding, this GO :0016887 : ATPase activity, this GO :0017046 : peptide hormone binding, this GO :0031626 : beta-endorphin binding, this GO :0042277 : peptide binding, this GO :0042803 : protein homodimerization activity, this GO :0043130 : ubiquitin binding, this GO :0043559 : insulin binding, this GO :0046872 : metal ion binding, insulin-degrading enzyme |
| Identity: |
5381 |
| Gene: |
IDE |
More about : IDE |
| Long gene name: |
insulin degrading enzyme |
| Synonyms gene name: |
insulin-degrading enzyme |
| Synonyms name: |
insulysin |
| Locus: |
10q23, 33 |
| Discovery year: |
1990-07-03 |
| GenBank acession: |
M21188 |
| Entrez gene record: |
3416 |
| Pubmed identfication: |
2293021 |
| RefSeq identity: |
NM_004969 |
| Havana BLAST/BLAT: |
OTTHUMG00000018759 |