| Alternative name 1: |
110kD, Clone: 51, Mab anti-Human, WB/NO IH, ERCC1/XPF Endonuclease Complex |
| Alternative name 2: |
110kD, Clone: 51, Mab antibody-Human, WB/NO IH, ERCC1/XPF Endonuclease Complex |
| Alternative name 3: |
110kD, Clone: 51, Mab antibody-Homo sapiens, WB/NO IH, ERCC1/XPF Endonuclease Complex |
| Alternative name 4: |
anti-ERCC1/XPF Endonuclease Complex 110kD Clone: 51 /NO |
| Alternative name 5: |
ERCC1/XPF Endonuclease Complex 110kD Clone: 51 /NO |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
110kD, 51, Monoclonal /NO IH, ERCC1/XPF Endonuclease Complex |
| Short name: |
110kD, Clone: 51, Mouse Monoclonal antibody- /NO IH, ERCC1/XPF Endonuclease Complex |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
110kD, Mouse monoclonal (Antibody to)-H, Western Blot/NO IH, clonality: 51, complementation family 1 (includes overlapping antisense sequence)/XPF Endonuclease aggregate, sapiens, excision repair cross-complementing rodent repair deficiency |
| Alternative technique: |
murine |
| Alternative to gene target: |
3'-to lesion and biological process this GO :0006296 and nucleotide-excision repair, 5'-to lesion and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006312 and mitotic recombination and biological process this GO :0006949 and syncytium formation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007281 and germ cell development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007584 and response to nutrient and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009650 and UV protection and biological process this GO :0009744 and response to sucrose stimulus and biological process this GO :0010165 and response to X-ray and biological process this GO :0010259 and multicellular organismal aging and biological process this GO :0017025 and TBP-class protein binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0032205 and negative regulation of telomere maintenance and biological process this GO :0035166 and post-embryonic hemopoiesis and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036297 and interstrand cross-link repair and biological process this GO :0043566 and structure-specific DNA binding and molecular function this GO :0045190 and isotype switching and biological process this GO :0048468 and cell development and biological process this GO :0048477 and oogenesis and biological process this GO :0048568 and embryonic organ development and biological process this GO :0051276 and chromosome organization and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, COFS4 and RAD10 and UV20, DNA damage removal and biological process this GO :0000720 and pyrimidine dimer repair by nucleotide-excision repair and biological process this GO :0000737 and DNA catabolic process, DNA incision, DNA incision, ERCC1 and IDBG-57509 and ENSG00000012061 and 2067, ERCC1 and IDBG-639466 and ENSBTAG00000017355 and 615637, Ercc1 and IDBG-150201 and ENSMUSG00000003549 and 13870, complementation group 1 (includes overlapping antisense sequence), endonucleolytic and biological process this GO :0000784 and nuclear chromosome, nuclei, structure-specific DNA binding, telomeric region and cellular component this GO :0001094 and TFIID-class transcription factor binding and molecular function this GO :0001302 and replicative cell aging and biological process this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0004519 and endonuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005669 and transcription factor TFIID complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006295 and nucleotide-excision repair, this GO :0000014 and single-stranded DNA endodeoxyribonuclease activity and molecular function this GO :0000109 and nucleotide-excision repair complex and cellular component this GO :0000718 and nucleotide-excision repair, this GO :0000014 : single-stranded DNA endodeoxyribonuclease activity, this GO :0000014 : single-stranded DNA endodeoxyribonuclease activity and also this GO :0001094 : TFIID-class transcription factor binding and also this GO :0003677 : DNA binding and also this GO :0003684 : damaged DNA binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0004519 : endonuclease activity and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0017025 : TBP-class protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0043566 : structure-specific DNA binding, this GO :0001094 : TFIID-class transcription factor binding, this GO :0003677 : DNA binding, this GO :0003684 : damaged DNA binding, this GO :0003697 : single-stranded DNA binding, this GO :0004519 : endonuclease activity, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0017025 : TBP-class protein binding, this GO :0019904 : protein domain specific binding, this GO :0043566 : structure-specific DNA binding, excision repair cross-complementing rodent repair deficiency |
| Identity: |
3433 |
| Gene: |
ERCC1 |
More about : ERCC1 |
| Long gene name: |
ERCC excision repair 1, endonuclease non-catalytic subunit |
| Synonyms gene name: |
complementation group 1 (includes overlapping antisense sequence) excision repair cross-complementation group 1 , excision repair cross-complementing rodent repair deficiency |
| Synonyms: |
RAD10 |
| Locus: |
19q13, 32 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2067 |
| Pubmed identfication: |
6462228 26939044 |
| RefSeq identity: |
NM_001983 |
| Classification: |
ERCC excision repair associated |
| Havana BLAST/BLAT: |
OTTHUMG00000182121 |