| Alternative name 1: |
Clone: ALK1, Mab anti-Human, paraffin (pretreat), Anaplastic Lymphoma Kinase (ALK) |
| Alternative name 2: |
Clone: ALK1, Mab antibody-Human, paraffin (pretreat), Anaplastic Lymphoma Kinase (ALK) |
| Alternative name 3: |
Clone: ALK1, Mab antibody-Homo sapiens, paraffin (pretreat), Anaplastic Lymphoma Kinase (ALK) |
| Alternative name 4: |
anti-Anaplastic Lymphoma Kinase ALK Clone: ALK1 pretreat |
| Alternative name 5: |
Anaplastic Lymphoma Kinase ALK Clone: ALK1 pretreat |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal paraffin (pretreat), Anaplastic Lymphoma Kinase (ALK) ALK1 |
| Short name: |
Mouse Monoclonal antibody- paraffin (pretreat), Anaplastic Lymphoma Kinase (ALK) Clone: ALK1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, paraffin |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
Mouse monoclonal (Antibody to)-H, clonality: ALK1, paraffin (pretreat), sapiens, Anaplastic Lymphoma phosphorylation catalyst (anaplastic lymphoma receptor tyrosine kinase) |
| Alternative technique: |
murine |
| Alternative to gene target: |
ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, Plasma membranes, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004704 : NF-kappaB-inducing kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004704 : NF-kappaB-inducing kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, anaplastic lymphoma receptor tyrosine kinase |
| Identity: |
175 |
| Gene: |
ACVRL1 |
More about : ACVRL1 |
| Long gene name: |
activin A receptor like type 1 |
| Synonyms gene: |
ACVRLK1 ORW2 |
| Synonyms gene name: |
activin A receptor type II-like 1 activin A receptor type IL |
| Synonyms: |
HHT2 ALK1 HHT |
| Locus: |
12q13, 13 |
| Discovery year: |
1994-12-12 |
| GenBank acession: |
L17075 |
| Entrez gene record: |
94 |
| Pubmed identfication: |
8397373 8640225 22718755 |
| RefSeq identity: |
NM_000020 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000169507 |
| Locus Specific Databases: |
Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database LRG_543 |