| Category: |
siRNA |
| Target: |
CFLAR |
| Immunogen: |
See techfile |
| Raised in: |
Synthetic |
| Reactivity: |
Mouse, Rat, Human |
| Purification: |
Affinity purified |
| Applications: |
WB (for other see techfile or inquire) |
| Stock availability: |
Shipped within 5-10 working days |
| Storage conditions: |
Avoid repeated freeze/thaw cycles, Aliquot and store at -20 °, C |
| Warnings: |
This product is for research use only |
| Gene target: |
CFLAR siRNA |
| Short name: |
Anti-CFLAR siRNA |
| Alternative name: |
member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator small interfearing RNA, antibody to-CASP8 and Fas (TNF receptor superfamily |
| Alternative to gene target: |
CFLAR and IDBG-78386 and ENSG00000003402 and 8837, FLIP and IDBG-643202 and ENSBTAG00000010998 and 497199, Plasma membranes, c-FLIP and c-FLIPL and c-FLIPR and c-FLIPS and CASH and CASP8AP1 and Casper and CLARP and FLAME and FLAME-1 and FLAME1 and FLIP and I-FLICE and MRIT, death effector domain binding, this GO :0002020 and protease binding and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014842 and regulation of satellite cell proliferation and biological process this GO :0014866 and skeletal myofibril assembly and biological process this GO :0016032 and viral process and biological process this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035877 and death effector domain binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0060544 and regulation of necroptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :1901740 and negative regulation of myoblast fusion and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005123 : death receptor binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0032403 : protein complex binding and also this GO :0035877 : death effector domain binding, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005123 : death receptor binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008234 : cysteine-type peptidase activity, this GO :0032403 : protein complex binding, this GO :0035877 : death effector domain binding, CASP8 and FADD-like apoptosis regulator |
| Identity: |
1876 |
| Gene: |
CFLAR |
More about : CFLAR |
| Long gene name: |
CASP8 and FADD like apoptosis regulator |
| Synonyms gene: |
CASP8AP1 |
| Synonyms gene name: |
CASP8 and FADD-like apoptosis regulator |
| Synonyms: |
CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP |
| Locus: |
2q33, 1 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AF005774 |
| Entrez gene record: |
8837 |
| Pubmed identfication: |
9208847 9217161 |
| RefSeq identity: |
NM_003879 |
| Classification: |
Endogenous ligands Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000132819 |