| Long name: |
CFLAR Antibody |
| Antigen: |
CFLAR |
| Synonim names: |
CASH, CASH, CASP8 and FADD-like apoptosis regulator subunit p12, CASP8 and FADD-like apoptosis regulator subunit p43, CASP8AP1, CLARP, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME-1, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, MRIT, Usurpin, c-FLIP, CASP8 and FADD-like apoptosis regulator |
| Other names: |
CASH, CASP8 and FADD-like apoptosis regulator, CASP8 and FADD-like apoptosis regulator, CASP8 and FADD-like apoptosis regulator, CASP8 and FADD-like apoptosis regulator subunit p12, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, FADD-like anti-apoptotic molecule, FADD-like antiapoptotic molecule 1, FADD-like antiapoptotic molecule 1, FLAME-1, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MACH-related inducer of toxicity, MRIT, UsurpinCleaved into the following 2 chains:CASP8 and FADD-like apoptosis regulator subunit p43, c-FLIP, caspase homolog, caspase-eight-related protein, caspase-like apoptosis regulatory protein, caspase-related inducer of apoptosis, cellular FLICE-like inhibitory protein, inhibitor of FLICE, usurpin beta, CASP8 and FADD-like apoptosis regulator isoform 1 |
| Gene name: |
CFLAR, CFLAR |
| Gene synonims: |
CASH, CASH, CASH, CASP8AP1, CASP8AP1, CFLAR, CLARP, CLARP, CLARP, Casper, Casper, FLAME, FLAME-1, FLAME-1, FLAME1, FLIP, I-FLICE, I-FLICE, MRIT, MRIT, MRIT, c-FLIP, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CFLAR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal Antibodies |
| Clone: |
Not applicable to Polyclonal Antibodies |
| Reacts with: |
Human (Homo sapiens) |
| Specificity: |
, CFLAR, CFLAR antibody detects endogenous levels of total CFLAR protein, This is an antibody designed to detect CFLAR |
| Purification method: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form/Appearance: |
0, 150mM NaCl, pH 7, 02% sodium azide and 50% glycerol, 4, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Concentration: |
Enquire us for detailed information on the concentration of this antibody |
| Storage, shipping and handling: |
Store at -20 degree C for 1 year |
| Applications: |
EIA, ELI-Spot, ELISA, IFA, Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24° |
| Gene target: |
CFLAR |
| Short name: |
Anti- CFLAR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member 6) (TNFRSF6)-associated via death domain-like apoptosis regulator (Antibody to), Antibody to CASP8 and Fas (TNF receptor superfamily |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CFLAR and IDBG-78386 and ENSG00000003402 and 8837, FLIP and IDBG-643202 and ENSBTAG00000010998 and 497199, Plasma membranes, c-FLIP and c-FLIPL and c-FLIPR and c-FLIPS and CASH and CASP8AP1 and Casper and CLARP and FLAME and FLAME-1 and FLAME1 and FLIP and I-FLICE and MRIT, death effector domain binding, this GO :0002020 and protease binding and molecular function this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0008047 and enzyme activator activity and molecular function this GO :0008234 and cysteine-type peptidase activity and molecular function this GO :0014732 and skeletal muscle atrophy and biological process this GO :0014842 and regulation of satellite cell proliferation and biological process this GO :0014866 and skeletal myofibril assembly and biological process this GO :0016032 and viral process and biological process this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035877 and death effector domain binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0060544 and regulation of necroptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :1901740 and negative regulation of myoblast fusion and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005123 : death receptor binding and also this GO :0005515 : protein binding and also this GO :0008047 : enzyme activator activity and also this GO :0008234 : cysteine-type peptidase activity and also this GO :0032403 : protein complex binding and also this GO :0035877 : death effector domain binding, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0005123 : death receptor binding, this GO :0005515 : protein binding, this GO :0008047 : enzyme activator activity, this GO :0008234 : cysteine-type peptidase activity, this GO :0032403 : protein complex binding, this GO :0035877 : death effector domain binding, CASP8 and FADD-like apoptosis regulator |
| Identity: |
1876 |
| Gene: |
CFLAR |
More about : CFLAR |
| Long gene name: |
CASP8 and FADD like apoptosis regulator |
| Synonyms gene: |
CASP8AP1 |
| Synonyms gene name: |
CASP8 and FADD-like apoptosis regulator |
| Synonyms: |
CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP |
| Locus: |
2q33, 1 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AF005774 |
| Entrez gene record: |
8837 |
| Pubmed identfication: |
9208847 9217161 |
| RefSeq identity: |
NM_003879 |
| Classification: |
Endogenous ligands Death effector domain containing Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000132819 |