| Category: |
siRNA |
| Antibody's target: |
PSEN1 |
| Immunogen: |
See techfile |
| The antibody was raised in: |
Synthetic |
| Reactivity: |
Mouse, Rat, Human |
| Purification: |
Affinity purified |
| Applications: |
WB (for other see techfile or inquire) |
| Stock availability: |
Shipped within 5-10 working days |
| Storage conditions: |
Avoid repeated freeze/thaw cycles, Aliquot and store at -20 °, C |
| Warnings: |
This product is for research use only |
| Gene target: |
PSEN1 siRNA |
| Short name: |
Anti-PSEN1 siRNA |
| Alternative name: |
antibody to-presenilin 1 small interfearing RNA |
| Alternative to gene target: |
AD3 and FAD and PS-1 and PS1 and S182, PSEN1 and IDBG-11235 and ENSG00000080815 and 5663, PSEN1 and IDBG-646832 and ENSBTAG00000011757 and 282705, Psen1 and IDBG-155522 and ENSMUSG00000019969 and 19164, cadherin binding, glutamatergic and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060075 and regulation of resting membrane potential and biological process this GO :0070588 and calcium ion transmembrane transport and biological process this GO :0070765 and gamma-secretase complex and cellular component this GO :2000059 and negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, nuclei, this GO :0000045 and autophagic vacuole assembly and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000139 and this GO lgi membrane and cellular component this GO :0000186 and activation of MAPKK activity and biological process this GO :0000776 and kinetochore and cellular component this GO :0001568 and blood vessel development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001756 and somitogenesis and biological process this GO :0001764 and neuron migration and biological process this GO :0001921 and positive regulation of receptor recycling and biological process this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001947 and heart looping and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002286 and T cell activation involved in immune response and biological process this GO :0002573 and myeloid leukocyte differentiation and biological process this GO :0004175 and endopeptidase activity and molecular function this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005262 and calcium channel activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005640 and nuclear outer membrane and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005765 and lysosomal membrane and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005790 and smooth endoplasmic reticulum and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005813 and centrosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006486 and protein glycosylation and biological process this GO :0006508 and proteolysis and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006839 and mitochondrial transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006914 and autophagy and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007175 and negative regulation of epidermal growth factor-activated receptor activity and biological process this GO :0007176 and regulation of epidermal growth factor-activated receptor activity and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0007611 and learning or memory and biological process this GO :0007613 and memory and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008233 and peptidase activity and molecular function this GO :0009791 and post-embryonic development and biological process this GO :0009986 and cell surface and cellular component this GO :0015031 and protein transport and biological process this GO :0015813 and L-glutamate transport and biological process this GO :0015871 and choline transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016080 and synaptic vesicle targeting and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016485 and protein processing and biological process this GO :0021795 and cerebral cortex cell migration and biological process this GO :0021870 and Cajal-Retzius cell differentiation and biological process this GO :0021904 and dorsal/ventral neural tube patterning and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0022008 and neurogenesis and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030018 and Z disc and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0030182 and neuron differentiation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0030900 and forebrain development and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031594 and neuromuscular junction and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032436 and positive regulation of proteasomal ubiquitin-dependent protein catabolic process and biological process this GO :0032469 and endoplasmic reticulum calcium ion homeostasis and biological process this GO :0034205 and beta-amyloid formation and biological process this GO :0035253 and ciliary rootlet and cellular component this GO :0035282 and segmentation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0040011 and locomotion and biological process this GO :0042325 and regulation of phosphorylation and biological process this GO :0042640 and anagen and biological process this GO :0042987 and amyloid precursor protein catabolic process and biological process this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043198 and dendritic shaft and cellular component this GO :0043227 and membrane-bounded organelle and cellular component this GO :0043234 and protein complex and cellular component this GO :0043393 and regulation of protein binding and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043589 and skin morphogenesis and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0045296 and cadherin binding and molecular function this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048538 and thymus development and biological process this GO :0048666 and neuron development and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048854 and brain morphogenesis and biological process this GO :0050435 and beta-amyloid metabolic process and biological process this GO :0050673 and epithelial cell proliferation and biological process this GO :0050771 and negative regulation of axonogenesis and biological process this GO :0050820 and positive regulation of coagulation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051444 and negative regulation of ubiquitin-protein transferase activity and biological process this GO :0051563 and smooth endoplasmic reticulum calcium ion homeostasis and biological process this GO :0051604 and protein maturation and biological process this GO :0051966 and regulation of synaptic transmission, this GO :0004175 : endopeptidase activity, this GO :0004175 : endopeptidase activity and also this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0005262 : calcium channel activity and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008233 : peptidase activity and also this GO :0030165 : PDZ domain binding and also this GO :0045296 : cadherin binding, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0005262 : calcium channel activity, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0008233 : peptidase activity, this GO :0030165 : PDZ domain binding, this GO :0045296 : cadherin binding, presenilin 1 |
| Identity: |
9508 |
| Gene: |
PSEN1 |
More about : PSEN1 |
| Long gene name: |
presenilin 1 |
| Synonyms gene: |
AD3 |
| Synonyms gene name: |
Alzheimer disease 3 |
| Synonyms: |
FAD S182 PS1 |
| Locus: |
14q24, 2 |
| Discovery year: |
1992-11-05 |
| GenBank acession: |
AJ008005 |
| Entrez gene record: |
5663 |
| Pubmed identfication: |
1411576 |
| RefSeq identity: |
NM_000021 |
| Havana BLAST/BLAT: |
OTTHUMG00000141279 |
| Locus Specific Databases: |
Alzheimer Disease &, Frontotemporal Dementia Mutation Database ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_224 |