| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Fc gamma RI is produced by our Mammalian expression system and the target gene encoding Gln16-Pro288 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
31, 7 kD |
| UniProt number: |
P12314 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
150 mM sodium chloride, pH7, 2 um filtered solution of 20 mM PB, 4, Lyophilized from a 0 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
QVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
CD64 (C-6His), FCGR1A, RI, Fc &gamma |
| Short name: |
CD64 (C-6His), FCGR1A, RI, Recombinant Fc &gamma |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans |
| Alternative name: |
CD64 (C-6His), RI, fragment c fragment on Immunoglobulin G, high affinity Ia, receptor (CD64), sapiens fragment c &gamma, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
CD64 and CD64A and FCRI and IGFR1, FCGR1A and IDBG-101961 and ENSG00000150337 and 2209, IgG binding, Plasma membranes, TAP-dependent and biological process this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006911 and pha this GO cytosis, engulfment and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019864 and IgG binding and molecular function this GO :0030669 and clathrin-coated endocytic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0045087 and innate immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process, high affinity Ia, receptor (CD64), this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005057 : receptor signaling protein activity, this GO :0005057 : receptor signaling protein activity and also this GO :0005515 : protein binding and also this GO :0019864 : IgG binding, this GO :0005515 : protein binding, this GO :0019864 : IgG binding, Fc fragment of IgG |
| Identity: |
3613 |
| Gene: |
FCGR1A |
More about : FCGR1A |
| Long gene name: |
Fc fragment of IgG receptor Ia |
| Synonyms gene name: |
Fc fragment of IgG, high affinity Ia, high affinity Ia, receptor (CD64) , receptor for (CD64) Fc fragment of IgG |
| Synonyms: |
CD64 CD64A |
| Synonyms name: |
Fc gamma receptor Ia |
| Locus: |
1q21, 2 |
| Discovery year: |
1992-12-03 |
| GenBank acession: |
BC032634 |
| Entrez gene record: |
2209 |
| Pubmed identfication: |
8697799 9763663 |
| RefSeq identity: |
NM_000566 |
| Classification: |
CD molecules Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000012089 |
| Locus Specific Databases: |
FCGR1Abase: Mutation registry for CD64 deficiency LRG_59 |