| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human IL-18 binding protein is produced by our Mammalian expression system and the target gene encoding Thr31-Gly194 is expressed with a Fc tag at the C-terminus |
| Molecular Weight: |
44, 7 kD |
| UniProt number: |
O95998 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
150 mM sodium chloride, 2, 2 um filtered solution of 20 mM PB, Lyophilized from a 0, pH7 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
TPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQEALPSSHSSPQQQGVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
IL18BP (C-Fc), Interleukin-18-Binding Protein |
| Short name: |
IL18BP (C-Fc), Recombinant Interleukin-18-Binding Protein |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
interleukin 18 binding protein (C-fragment c), sapiens Interleukin-18-Binding Protein, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
Extracellular, IL18BP and IDBG-62960 and ENSG00000137496 and 10068, IL18BP and IDBG-634897 and ENSBTAG00000027676 and 617470, IL18BPa, Il18bp and IDBG-202395 and ENSMUSG00000070427 and 16068, receptor anta this GO nist activity, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0042007 and interleukin-18 binding and molecular function this GO :0042088 and T-helper 1 type immune response and biological process this GO :0048019 and receptor anta this GO nist activity and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :1900116 and extracellular negative regulation of signal transduction and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0042007 : interleukin-18 binding and also this GO :0048019 : receptor anta this GO nist activity, this GO :0042007 : interleukin-18 binding, this GO :0048019 : receptor anta this GO nist activity, interleukin 18 binding protein |
| Identity: |
5987 |
| Gene: |
IL18BP |
More about : IL18BP |
| Long gene name: |
interleukin 18 binding protein |
| Synonyms: |
IL18BPa |
| Synonyms name: |
MC51L-53L-54L homolog gene product |
| Locus: |
11q13, 4 |
| Discovery year: |
1999-05-21 |
| GenBank acession: |
AF110798 |
| Entrez gene record: |
10068 |
| Pubmed identfication: |
10023777 |
| RefSeq identity: |
NM_173042 |
| Classification: |
Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133713 |