| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human jagged-1 is produced by our Mammalian expression system and the target gene encoding Gln34-Ser1046 is expressed with a Fc tag at the C-terminus |
| Molecular Weight: |
138, 5 kD |
| UniProt number: |
P78504 |
| State of the product: |
Freeze-dried |
| Shipping conditions: |
Ambient temperature |
| Formulation: |
2 um filtered solution of phosphate buffered saline, 4, Lyophilized from a 0, pH7 |
| Storage recommendations: |
-20°, Aliquots of reconstituted samples are stable at less -20°, If kept at at room temperature, If kept at at room temperature, Reconstituted protein solution should be stored at 4-7°, it is stable for 3 weeks, it is stable for 3 weeks, C, C for 2-7 days, C for 3 months, Freeze-dried proteins should be stored frozen at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
QFELEILSMQNVNGELQNGNCCGGARNPGDRKCTRDECDTYFKVCLKEYQSRVTAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFAWPRSYTLLVEAWDSSNDTVQPDSIIEKASHSGMINPSRQWQTLKQNTGVAHFEYQIRVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCTSDSYYQDNCANITFTFNKEMMSPGLTTEHICSELRNLNILKNVSAEYSIYIACEPSPSANNEIHVAISAEDIRDDGNPIKEITDKIIDLVSKRDGNSVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
CD339 (C-Fc), JAG1, Jagged-1 |
| Short name: |
CD339 (C-Fc), JAG1, Recombinant Jagged-1 |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans, Human |
| Alternative name: |
CD339 (C-fragment c), jagged 1, sapiens Jagged-1, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
AGS and AHD and AWS and CD339 and HJ1 and JAGL1, Extracellular, JAG1 and IDBG-54207 and ENSG00000101384 and 182, JAG1 and IDBG-636477 and ENSBTAG00000012817 and 783681, Jag1 and IDBG-207934 and ENSMUSG00000027276 and 16449, growth factor activity, this GO :0001525 and angiogenesis and biological process this GO :0001709 and cell fate determination and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002011 and morphogenesis of an epithelial sheet and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0003184 and pulmonary valve morphogenesis and biological process this GO :0003215 and cardiac right ventricle morphogenesis and biological process this GO :0005112 and Notch binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007154 and cell communication and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0007220 and Notch receptor processing and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007399 and nervous system development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0009887 and organ morphogenesis and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0035909 and aorta morphogenesis and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042491 and auditory receptor cell differentiation and biological process this GO :0043010 and camera-type eye development and biological process this GO :0045177 and apical part of cell and cellular component this GO :0045445 and myoblast differentiation and biological process this GO :0045446 and endothelial cell differentiation and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045639 and positive regulation of myeloid cell differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048839 and inner ear development and biological process this GO :0060411 and cardiac septum morphogenesis and biological process this GO :0061073 and ciliary body morphogenesis and biological process this GO :0061156 and pulmonary artery morphogenesis and biological process this GO :0061309 and cardiac neural crest cell development involved in outflow tract morphogenesis and biological process this GO :0061314 and Notch signaling involved in heart development and biological process this GO :0061444 and endocardial cushion cell development and biological process this GO :0072017 and distal tubule development and biological process this GO :0072070 and loop of Henle development and biological process this GO :0097150 and neuronal stem cell maintenance and biological process this GO :2000737 and negative regulation of stem cell differentiation and biological process, this GO :0005112 : Notch binding, this GO :0005112 : Notch binding and also this GO :0005198 : structural molecule activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity, this GO :0005198 : structural molecule activity, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, jagged 1 |
| Identity: |
6188 |
| Gene: |
JAG1 |
More about : JAG1 |
| Long gene name: |
jagged 1 |
| Synonyms gene: |
AGS JAGL1 |
| Synonyms gene name: |
Alagille syndrome |
| Synonyms: |
AHD AWS HJ1 CD339 |
| Locus: |
20p12, 2 |
| Discovery year: |
1997-05-22 |
| GenBank acession: |
U61276 |
| Entrez gene record: |
182 |
| Pubmed identfication: |
7697721 9207788 |
| RefSeq identity: |
NM_000214 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000031872 |
| Locus Specific Databases: |
JAG1 database at LOVD-China |