| Reacts with: |
Human |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Human Tropomyosin alpha-1 is produced by our E, coli expression system and the target gene encoding Met1-Met284 is expressed with a 6His tag at the N-terminus |
| Molecular Weight: |
35 kD |
| UniProt number: |
P09493 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry ice/ice packs |
| Formulation: |
1 mM DTT, 100 mM sodium chloride, 20% Glycerol, pH 8, 0 , 2 um filtered solution of 20 mM Tris, Supplied as a 0 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Avoid mixing using vortex or pipettes, Dissolve the protein in ddH2O, In order to retain the quality and the affinity of the product unchanged, It is not recommended to dilute the product to less than 100 &mu, avoid cycles of freezing and thawing, please, The vials should be centrifuged before it is opened, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
MGSSHHHHHHSSGLVPRGSHMDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSM |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Group: |
recombinants |
| Gene target: |
TPM1 (N-6His), -1 Chain, Tropomyosin &alpha |
| Short name: |
TPM1 (N-6His), -1 Chain, Recombinant Tropomyosin &alpha |
| Technique: |
E, coli recombinant proteins are , novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Humans |
| Alternative name: |
sapiens Tropomyosin &alpha, tropomyosin 1 (alpha) (N-6His), -1 epitope, recombinant H |
| Alternative technique: |
rec |
| Alternative to gene target: |
C15orf13 and CMD1Y and CMH3 and HTM-alpha and LVNC9 and TMSA, Cytoplasm, TPM1 and IDBG-15400 and ENSG00000140416 and 7168, TPM1 and IDBG-646543 and ENSBTAG00000005373 and 281544, Tpm1 and IDBG-180208 and ENSMUSG00000032366 and 22003, structural constituent of muscle, this GO :0001701 and in utero embryonic development and biological process this GO :0001725 and stress fiber and cellular component this GO :0003065 and positive regulation of heart rate by epinephrine and biological process this GO :0003779 and actin binding and molecular function this GO :0005200 and structural constituent of cytoskeleton and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005862 and muscle thin filament tropomyosin and cellular component this GO :0006928 and cellular component movement and biological process this GO :0006936 and muscle contraction and biological process this GO :0006937 and regulation of muscle contraction and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0008016 and regulation of heart contraction and biological process this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008307 and structural constituent of muscle and molecular function this GO :0030016 and myofibril and cellular component this GO :0030017 and sarcomere and cellular component this GO :0030049 and muscle filament sliding and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0031529 and ruffle organization and biological process this GO :0031941 and filamentous actin and cellular component this GO :0032059 and bleb and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0032781 and positive regulation of ATPase activity and biological process this GO :0034614 and cellular response to reactive oxygen species and biological process this GO :0042060 and wound healing and biological process this GO :0045214 and sarcomere organization and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0055010 and ventricular cardiac muscle tissue morphogenesis and biological process this GO :0060048 and cardiac muscle contraction and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005200 : structural constituent of cytoskeleton and also this GO :0008092 : cytoskeletal protein binding and also this GO :0008307 : structural constituent of muscle, this GO :0005200 : structural constituent of cytoskeleton, this GO :0008092 : cytoskeletal protein binding, this GO :0008307 : structural constituent of muscle, tropomyosin 1 (alpha) |
| Identity: |
12010 |
| Gene: |
TPM1 |
More about : TPM1 |
| Long gene name: |
tropomyosin 1 (alpha) |
| Synonyms gene: |
C15orf13 CMH3 |
| Synonyms gene name: |
chromosome 15 open reading frame 13 cardiomyopathy, hypertrophic 3 |
| Locus: |
15q22, 2 |
| Discovery year: |
1991-07-18 |
| GenBank acession: |
AB209041 |
| Entrez gene record: |
7168 |
| Pubmed identfication: |
10343096 8205619 |
| RefSeq identity: |
NM_001018004 |
| Classification: |
Tropomyosins |
| Havana BLAST/BLAT: |
OTTHUMG00000132803 |
| Locus Specific Databases: |
FHC Mutation Database LRG_387 |