| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PACSIN2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IF, IHC-P, WB |
| Recommended dilutions: |
IHC (FFPE): 1:50-100, Immunofluorescence: 1:100, Western blot: 1:500-1:1000 |
| Intented use: |
This PACSIN2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UNF0 |
| Purity: |
Protein G affinity chromatography |
| Description: |
Involved in the endocytosis of cell-surface receptors like the EGF receptor, May also play a role in the formation of caveolae at the cell membrane, Plays a role in intracellular vesicle- mediated transport, Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis, contributing to its internalization in the absence of EGF stimulus, Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds |
| Immunogen: |
A portion of amino acids 342-371 from the human protein was used as the immunogen for the PACSIN2 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the PACSIN2 antibody and store frozen at -20 deg |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PACSIN2 |
| Short name: |
PACSIN2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
protein phosphorylation catalyst C and casein phosphorylation catalyst substrate in neurons 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PACSIN2 and IDBG-10313 and ENSG00000100266 and 11252, PACSIN2 and IDBG-642127 and ENSBTAG00000019290 and 540107, Pacsin2 and IDBG-168133 and ENSMUSG00000016664 and 23970, SDPII, nuclei, phosphatidic acid binding, this GO :0005215 and transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005901 and caveola and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0008092 and cytoskeletal protein binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0019898 and extrinsic component of membrane and cellular component this GO :0030036 and actin cytoskeleton organization and biological process this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0036010 and protein localization to endosome and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045806 and negative regulation of endocytosis and biological process this GO :0048858 and cell projection morphogenesis and biological process this GO :0055038 and recycling endosome membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070300 and phosphatidic acid binding and molecular function this GO :0070836 and caveola assembly and biological process this GO :0072584 and caveolin-mediated endocytosis and biological process this GO :0097320 and membrane tubulation and biological process, this GO :0005215 : transporter activity, this GO :0005215 : transporter activity and also this GO :0005515 : protein binding and also this GO :0008092 : cytoskeletal protein binding and also this GO :0008289 : lipid binding and also this GO :0042802 : identical protein binding and also this GO :0070300 : phosphatidic acid binding, this GO :0005515 : protein binding, this GO :0008092 : cytoskeletal protein binding, this GO :0008289 : lipid binding, this GO :0042802 : identical protein binding, this GO :0070300 : phosphatidic acid binding, protein kinase C and casein kinase substrate in neurons 2 |
| Identity: |
8571 |
| Gene: |
PACSIN2 |
More about : PACSIN2 |
| Long gene name: |
protein kinase C and casein kinase substrate in neurons 2 |
| Synonyms: |
SDPII |
| Synonyms name: |
syndapin II |
| Locus: |
22q13, 2 |
| Discovery year: |
1999-10-12 |
| GenBank acession: |
AF128536 |
| Entrez gene record: |
11252 |
| Pubmed identfication: |
10431838 11082044 |
| RefSeq identity: |
NM_007229 |
| Classification: |
F-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150701 |