| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Kindlin-3 / URP2 / FERMT3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 1:1000-2000 |
| Intented use: |
This Kindlin-3 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
83706 |
| Uniprot #: |
Q86UX7 |
| Purity: |
Antigen affinity |
| Description: |
Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3), Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity), Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells, Fermitin family homolog 3 |
| Immunogen: |
A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Kindlin-3 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Kindlin-3 / URP2 / FERMT3 |
| Short name: |
Kindlin-3 Antibody / URP2 / FERMT3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Kindlin-3 (Antibody to) / URP2 / fermitin family member 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, FERMT3 and IDBG-53150 and ENSG00000149781 and 83706, FERMT3 and IDBG-643881 and ENSBTAG00000045862 and 525159, Fermt3 and IDBG-137957 and ENSMUSG00000024965 and 108101, protein binding, this GO :0002102 and podosome and cellular component this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0030054 and cell junction and cellular component this GO :0033622 and integrin activation and biological process this GO :0033632 and regulation of cell-cell adhesion mediated by integrin and biological process this GO :0034446 and substrate adhesion-dependent cell spreading and biological process this GO :0042995 and cell projection and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, fermitin family member 3 |
| Identity: |
23151 |
| Gene: |
FERMT3 |
More about : FERMT3 |
| Long gene name: |
fermitin family member 3 |
| Synonyms gene name: |
fermitin family homolog 3 (Drosophila) |
| Synonyms: |
URP2 KIND3 MIG2B MGC10966 MIG-2 UNC112C |
| Synonyms name: |
kindlin-3 |
| Locus: |
11q13, 1 |
| Discovery year: |
2007-12-14 |
| GenBank acession: |
L25343 |
| Entrez gene record: |
83706 |
| RefSeq identity: |
NM_031471 |
| Classification: |
Fermitins Pleckstrin homology domain containing FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167790 |
| Locus Specific Databases: |
LRG_180 |